RYBP (RING1 and YY1 binding protein)

2007-02-01  

Identity

HGNC
RYBP
LOCATION
3p13
LOCUSID
23429
ALIAS
AAP1,APAP-1,DEDAF,YEAF1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23429
MIM: 607535
HGNC: 10480
Ensembl: ENSG00000163602

Variants:

dbSNP: 23429
ClinVar: 23429
TCGA: ENSG00000163602
COSMIC: RYBP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163602ENST00000477973Q8N488

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
387352052024Glucose-induced RYBP suppresses tumor cell aerobic glycolysis and migration.0
387352052024Glucose-induced RYBP suppresses tumor cell aerobic glycolysis and migration.0
372727522023Deficiency of the Polycomb Protein RYBP and TET Methylcytosine Oxidases Promotes Extensive CpG Island Hypermethylation and Malignant Transformation.1
372727522023Deficiency of the Polycomb Protein RYBP and TET Methylcytosine Oxidases Promotes Extensive CpG Island Hypermethylation and Malignant Transformation.1
359089532022Re-expression of circ_0043610 contributes to trophoblast dysfunction through the miR-558/RYBP pathway in preeclampsia.1
362330632022RYBP Sensitizes Cancer Cells to PARP Inhibitors by Regulating ATM Activity.0
359089532022Re-expression of circ_0043610 contributes to trophoblast dysfunction through the miR-558/RYBP pathway in preeclampsia.1
362330632022RYBP Sensitizes Cancer Cells to PARP Inhibitors by Regulating ATM Activity.0
335378352021Upregulated miR‑411‑5p levels promote lymph node metastasis by targeting RYBP in head and neck squamous cell carcinoma.4
339458882021The nuclear localization sequence of the epigenetic factor RYBP binds to human importin α3.4
335378352021Upregulated miR‑411‑5p levels promote lymph node metastasis by targeting RYBP in head and neck squamous cell carcinoma.4
339458882021The nuclear localization sequence of the epigenetic factor RYBP binds to human importin α3.4
322094262020RYBP inhibits esophageal squamous cell carcinoma proliferation through downregulating CDC6 and CDC45 in G1-S phase transition process.9
322094262020RYBP inhibits esophageal squamous cell carcinoma proliferation through downregulating CDC6 and CDC45 in G1-S phase transition process.9
300404872019RYBP modulates stability and function of Ring1B through targeting UBE3A.2

Citation

Dessen P

RYBP (RING1 and YY1 binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43694/cancer-prone-explorer/teaching-explorer/css/card-gene.css