RYBP (RING1 and YY1 binding protein)

2007-02-01  

Identity

HGNC
LOCATION
3p13
LOCUSID
ALIAS
AAP1,APAP-1,DEDAF,YEAF1
FUSION GENES

Other Information

Locus ID:

NCBI: 23429
MIM: 607535
HGNC: 10480
Ensembl: ENSG00000163602

Variants:

dbSNP: 23429
ClinVar: 23429
TCGA: ENSG00000163602
COSMIC: RYBP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163602ENST00000477973Q8N488

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
387352052024Glucose-induced RYBP suppresses tumor cell aerobic glycolysis and migration.0
387352052024Glucose-induced RYBP suppresses tumor cell aerobic glycolysis and migration.0
372727522023Deficiency of the Polycomb Protein RYBP and TET Methylcytosine Oxidases Promotes Extensive CpG Island Hypermethylation and Malignant Transformation.1
372727522023Deficiency of the Polycomb Protein RYBP and TET Methylcytosine Oxidases Promotes Extensive CpG Island Hypermethylation and Malignant Transformation.1
359089532022Re-expression of circ_0043610 contributes to trophoblast dysfunction through the miR-558/RYBP pathway in preeclampsia.1
362330632022RYBP Sensitizes Cancer Cells to PARP Inhibitors by Regulating ATM Activity.0
359089532022Re-expression of circ_0043610 contributes to trophoblast dysfunction through the miR-558/RYBP pathway in preeclampsia.1
362330632022RYBP Sensitizes Cancer Cells to PARP Inhibitors by Regulating ATM Activity.0
335378352021Upregulated miR‑411‑5p levels promote lymph node metastasis by targeting RYBP in head and neck squamous cell carcinoma.4
339458882021The nuclear localization sequence of the epigenetic factor RYBP binds to human importin α3.4
335378352021Upregulated miR‑411‑5p levels promote lymph node metastasis by targeting RYBP in head and neck squamous cell carcinoma.4
339458882021The nuclear localization sequence of the epigenetic factor RYBP binds to human importin α3.4
322094262020RYBP inhibits esophageal squamous cell carcinoma proliferation through downregulating CDC6 and CDC45 in G1-S phase transition process.9
322094262020RYBP inhibits esophageal squamous cell carcinoma proliferation through downregulating CDC6 and CDC45 in G1-S phase transition process.9
300404872019RYBP modulates stability and function of Ring1B through targeting UBE3A.2

Citation

Dessen P

RYBP (RING1 and YY1 binding protein)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43694/cancer-prone-explorer/teaching-explorer/js/_common.js