KCNK9 (potassium two pore domain channel subfamily K member 9)

2007-02-01  

Identity

HGNC
KCNK9
LOCATION
8q24.3
LOCUSID
51305
ALIAS
BIBARS,K2p9.1,KT3.2,TASK-3,TASK3,TASK32
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51305
MIM: 605874
HGNC: 6283
Ensembl: ENSG00000169427

Variants:

dbSNP: 51305
ClinVar: 51305
TCGA: ENSG00000169427
COSMIC: KCNK9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169427ENST00000303015Q9NPC2
ENSG00000169427ENST00000303015A0A024R9H3
ENSG00000169427ENST00000520439Q9NPC2
ENSG00000169427ENST00000520439A0A024R9H3
ENSG00000169427ENST00000522317Q9NPC2
ENSG00000169427ENST00000522317A0A024R9H3
ENSG00000169427ENST00000647605A0A3B3ITR0
ENSG00000169427ENST00000648164Q9NPC2
ENSG00000169427ENST00000648164A0A024R9H3
ENSG00000169427ENST00000649473A0A3B3IU12
ENSG00000169427ENST00000649696A0A3B3ITR0
ENSG00000169427ENST00000650269Q9NPC2
ENSG00000169427ENST00000650269A0A024R9H3

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Potassium ChannelsREACTOMER-HSA-1296071
Tandem pore domain potassium channelsREACTOMER-HSA-1296346
TWIK-releated acid-sensitive K+ channel (TASK)REACTOMER-HSA-1299316
Muscle contractionREACTOMER-HSA-397014
Aldosterone synthesis and secretionKEGGhsa04925
Aldosterone synthesis and secretionKEGGko04925
Cardiac conductionREACTOMER-HSA-5576891
Phase 4 - resting membrane potentialREACTOMER-HSA-5576886

References

Pubmed IDYearTitleCitations
386307232024C-type inactivation and proton modulation mechanisms of the TASK3 channel.0
386307232024C-type inactivation and proton modulation mechanisms of the TASK3 channel.0
356826532022Epigenomic Analysis Reveals the KCNK9 Potassium Channel as a Potential Therapeutic Target for Adenomyosis.1
356982422022Gain and loss of TASK3 channel function and its regulation by novel variation cause KCNK9 imprinting syndrome.3
366137872022Subcellular Localization of Homomeric TASK3 Channels and Its Presumed Functional Significances in Trigeminal Motoneurons.0
356826532022Epigenomic Analysis Reveals the KCNK9 Potassium Channel as a Potential Therapeutic Target for Adenomyosis.1
356982422022Gain and loss of TASK3 channel function and its regulation by novel variation cause KCNK9 imprinting syndrome.3
366137872022Subcellular Localization of Homomeric TASK3 Channels and Its Presumed Functional Significances in Trigeminal Motoneurons.0
3420229620215-(Indol-2-yl)pyrazolo[3,4-b]pyridines as a New Family of TASK-3 Channel Blockers: A Pharmacophore-Based Regioselective Synthesis.1
350115892021Expression of Proton-Sensitive GPR31, GPR151, TASK1 and TASK3 in Common Skin Tumors.3
3420229620215-(Indol-2-yl)pyrazolo[3,4-b]pyridines as a New Family of TASK-3 Channel Blockers: A Pharmacophore-Based Regioselective Synthesis.1
350115892021Expression of Proton-Sensitive GPR31, GPR151, TASK1 and TASK3 in Common Skin Tumors.3
314237442020Effects of the ventilatory stimulant, doxapram on human TASK-3 (KCNK9, K2P9.1) channels and TASK-1 (KCNK3, K2P3.1) channels.6
314237442020Effects of the ventilatory stimulant, doxapram on human TASK-3 (KCNK9, K2P9.1) channels and TASK-1 (KCNK3, K2P3.1) channels.6
318102252019TASK-3 Gene Knockdown Dampens Invasion and Migration and Promotes Apoptosis in KATO III and MKN-45 Human Gastric Adenocarcinoma Cell Lines.14

Citation

Dessen P

KCNK9 (potassium two pore domain channel subfamily K member 9)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43764/case-report-explorer/favicon/css/card-gene.css