NANOS1 (nanos C2HC-type zinc finger 1)

2007-02-01  

Identity

HGNC
LOCATION
10q26.11
LOCUSID
ALIAS
EC_Rep1a,NOS-1,NOS1,SPGF12,ZC2HC12A

Other Information

Locus ID:

NCBI: 340719
MIM: 608226
HGNC: 23044
Ensembl: ENSG00000188613

Variants:

dbSNP: 340719
ClinVar: 340719
TCGA: ENSG00000188613
COSMIC: NANOS1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000188613ENST00000340087Q5T9H5
ENSG00000188613ENST00000425699Q8WY41

Expression (GTEx)

0
1
2
3
4
5
6
7

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
218001632011NANOS1 and PUMILIO2 bind microRNA biogenesis factor GEMIN3, within chromatoid body in human germ cells.12
182236802008The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression.11
191685462009The SNARE-associated component SNAPIN binds PUMILIO2 and NANOS1 proteins in human male germ cells.3
233200862013Genetic variants in meiotic program initiation pathway genes are associated with spermatogenic impairment in a Han Chinese population.3
170470632006E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion.0
233155412013Mutations of NANOS1, a human homologue of the Drosophila morphogen, are associated with a lack of germ cells in testes or severe oligo-astheno-teratozoospermia.0
251007352014Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells.0

Citation

Dessen P

NANOS1 (nanos C2HC-type zinc finger 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43992/nanos1