MEAF6 (MYST/Esa1 associated factor 6)

2005-02-01  

Identity

HGNC
LOCATION
1p34.3
LOCUSID
ALIAS
C1orf149,CENP-28,EAF6,NY-SAR-91
FUSION GENES

Other Information

Locus ID:

NCBI: 64769
MIM: 611001
HGNC: 25674
Ensembl: ENSG00000163875

Variants:

dbSNP: 64769
ClinVar: 64769
TCGA: ENSG00000163875
COSMIC: MEAF6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163875ENST00000296214Q9HAF1
ENSG00000163875ENST00000373073Q9HAF1
ENSG00000163875ENST00000373074B1AK63
ENSG00000163875ENST00000373075Q9HAF1
ENSG00000163875ENST00000448519Q9HAF1

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional Regulation by TP53REACTOMER-HSA-3700989
Chromatin organizationREACTOMER-HSA-4839726
Chromatin modifying enzymesREACTOMER-HSA-3247509
HATs acetylate histonesREACTOMER-HSA-3214847
Regulation of TP53 ActivityREACTOMER-HSA-5633007
Regulation of TP53 Activity through AcetylationREACTOMER-HSA-6804758

References

Pubmed IDYearTitleCitations
242854342014Novel ZC3H7B-BCOR, MEAF6-PHF1, and EPC1-PHF1 fusions in ossifying fibromyxoid tumors--molecular characterization shows genetic overlap with endometrial stromal sarcoma.30
245302302014MEAF6/PHF1 is a recurrent gene fusion in endometrial stromal sarcoma.16
284271942017Alternative RNA splicing of the MEAF6 gene facilitates neuroendocrine prostate cancer progression.8

Citation

Dessen P

MEAF6 (MYST/Esa1 associated factor 6)

Atlas Genet Cytogenet Oncol Haematol. 2005-02-01

Online version: http://atlasgeneticsoncology.org/gene/45510/meaf6-(myst-esa1-associated-factor-6)