TRIM36 (tripartite motif containing 36)

2007-02-01  

Identity

HGNC
TRIM36
LOCATION
5q22.3
LOCUSID
55521
ALIAS
ANPH,HAPRIN,RBCC728,RNF98
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55521
MIM: 609317
HGNC: 16280
Ensembl: ENSG00000152503

Variants:

dbSNP: 55521
ClinVar: 55521
TCGA: ENSG00000152503
COSMIC: TRIM36

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000152503ENST00000282369Q9NQ86
ENSG00000152503ENST00000379617Q9NQ86
ENSG00000152503ENST00000379618Q9NQ86
ENSG00000152503ENST00000508894D6RAU9
ENSG00000152503ENST00000513154Q9NQ86
ENSG00000152503ENST00000514154E9PBG3

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
192325192009TRIM36 interacts with the kinetochore protein CENP-H and delays cell cycle progression.14
151450532004Cloning and characterisation of the RBCC728/TRIM36 zinc-binding protein from the tumor suppressor gene region at chromosome 5q22.3.11
294495342018TRIM36, a novel androgen-responsive gene, enhances anti-androgen efficacy against prostate cancer by inhibiting MAPK/ERK signaling pathways.11
302386872018Androgen-responsive tripartite motif 36 enhances tumor-suppressive effect by regulating apoptosis-related pathway in prostate cancer.6
159558912005Identification of human HAPRIN potentially involved in the acrosome reaction.5
280877372017A homozygous mutation in TRIM36 causes autosomal recessive anencephaly in an Indian family.2
280877372017A homozygous mutation in TRIM36 causes autosomal recessive anencephaly in an Indian family.2
283599762017TRIM36 hypermethylation is involved in polycyclic aromatic hydrocarbons-induced cell transformation.1

Citation

Dessen P

TRIM36 (tripartite motif containing 36)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45556/trim36