RNH1 (ribonuclease/angiogenin inhibitor 1)

2007-02-01  

Identity

HGNC
RNH1
LOCATION
11p15.5
LOCUSID
6050
ALIAS
RAI,RNH
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 6050
MIM: 173320
HGNC: 10074
Ensembl: ENSG00000023191

Variants:

dbSNP: 6050
ClinVar: 6050
TCGA: ENSG00000023191
COSMIC: RNH1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000023191ENST00000354420P13489
ENSG00000023191ENST00000354420A0A140VJT8
ENSG00000023191ENST00000356187P13489
ENSG00000023191ENST00000356187A0A140VJT8
ENSG00000023191ENST00000397604P13489
ENSG00000023191ENST00000397604A0A140VJT8
ENSG00000023191ENST00000397614P13489
ENSG00000023191ENST00000397614A0A140VJT8
ENSG00000023191ENST00000397615P13489
ENSG00000023191ENST00000397615A0A140VJT8
ENSG00000023191ENST00000438658P13489
ENSG00000023191ENST00000438658A0A140VJT8
ENSG00000023191ENST00000524464E9PMA9
ENSG00000023191ENST00000525701E9PR82
ENSG00000023191ENST00000527485E9PIM9
ENSG00000023191ENST00000529115E9PMN0
ENSG00000023191ENST00000529306E9PMJ3
ENSG00000023191ENST00000529368E9PLZ3
ENSG00000023191ENST00000529768H0YCR7
ENSG00000023191ENST00000531149E9PIK5
ENSG00000023191ENST00000531540A0A0J9YXC4
ENSG00000023191ENST00000532055E9PMI1
ENSG00000023191ENST00000533410P13489
ENSG00000023191ENST00000533410A0A140VJT8
ENSG00000023191ENST00000534797P13489
ENSG00000023191ENST00000534797A0A140VJT8

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
387832412024New link between RNH1 and E2F1: regulates the development of lung adenocarcinoma.1
387832412024New link between RNH1 and E2F1: regulates the development of lung adenocarcinoma.1
369354172023Ribonuclease inhibitor 1 (RNH1) deficiency cause congenital cataracts and global developmental delay with infection-induced psychomotor regression and anemia.7
371910942023Biallelic variants in ribonuclease inhibitor (RNH1), an inflammasome modulator, are associated with a distinctive subtype of acute, necrotizing encephalopathy.1
375373372023Functional status analysis of RNH1 in bladder cancer for predicting immunotherapy response.0
369354172023Ribonuclease inhibitor 1 (RNH1) deficiency cause congenital cataracts and global developmental delay with infection-induced psychomotor regression and anemia.7
371910942023Biallelic variants in ribonuclease inhibitor (RNH1), an inflammasome modulator, are associated with a distinctive subtype of acute, necrotizing encephalopathy.1
375373372023Functional status analysis of RNH1 in bladder cancer for predicting immunotherapy response.0
352565132022LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity.8
352565132022LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity.8
335254752021Angiogenin (ANG)-Ribonuclease Inhibitor (RNH1) System in Protein Synthesis and Disease.0
335254752021Angiogenin (ANG)-Ribonuclease Inhibitor (RNH1) System in Protein Synthesis and Disease.0
294088052018Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation.13
301098132018Regulation of IRE1 RNase activity by the Ribonuclease inhibitor 1 (RNH1).8
294088052018Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation.13

Citation

Dessen P

RNH1 (ribonuclease/angiogenin inhibitor 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45618/favicon/js/web-card-gene.js