CBX1 (chromobox 1)

2007-02-01  

Identity

HGNC
LOCATION
17q21.32
LOCUSID
ALIAS
CBX,HP1-BETA,HP1Hs-beta,HP1Hsbeta,M31,MOD1,p25beta
FUSION GENES

Other Information

Locus ID:

NCBI: 10951
MIM: 604511
HGNC: 1551
Ensembl: ENSG00000108468

Variants:

dbSNP: 10951
ClinVar: 10951
TCGA: ENSG00000108468
COSMIC: CBX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108468ENST00000225603P83916
ENSG00000108468ENST00000225603Q6IBN6
ENSG00000108468ENST00000393408P83916
ENSG00000108468ENST00000393408Q6IBN6
ENSG00000108468ENST00000402583B5MD17
ENSG00000108468ENST00000444685C9JWS9
ENSG00000108468ENST00000495350K7ELA4
ENSG00000108468ENST00000581003J3KS05

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
363101392022N(6) -Methyladenosine-Modified CBX1 Regulates Nasopharyngeal Carcinoma Progression Through Heterochromatin Formation and STAT1 Activation.5
363101392022N(6) -Methyladenosine-Modified CBX1 Regulates Nasopharyngeal Carcinoma Progression Through Heterochromatin Formation and STAT1 Activation.5
334606842021Beyond the Nucleosome: Nucleosome-Protein Interactions and Higher Order Chromatin Structure.5
336611002021HP1 proteins compact DNA into mechanically and positionally stable phase separated domains.81
334606842021Beyond the Nucleosome: Nucleosome-Protein Interactions and Higher Order Chromatin Structure.5
336611002021HP1 proteins compact DNA into mechanically and positionally stable phase separated domains.81
315333402019DNA Damage Changes Distribution Pattern and Levels of HP1 Protein Isoforms in the Nucleolus and Increases Phosphorylation of HP1β-Ser88.6
315333402019DNA Damage Changes Distribution Pattern and Levels of HP1 Protein Isoforms in the Nucleolus and Increases Phosphorylation of HP1β-Ser88.6
282233592017Peptide recognition by heterochromatin protein 1 (HP1) chromoshadow domains revisited: Plasticity in the pseudosymmetric histone binding site of human HP1.16
282233592017Peptide recognition by heterochromatin protein 1 (HP1) chromoshadow domains revisited: Plasticity in the pseudosymmetric histone binding site of human HP1.16
270904912016Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin.65
270904912016Dynamic and flexible H3K9me3 bridging via HP1β dimerization establishes a plastic state of condensed chromatin.65
257690252015HP1β is a biomarker for breast cancer prognosis and PARP inhibitor therapy.22
257690252015HP1β is a biomarker for breast cancer prognosis and PARP inhibitor therapy.22
245611992014Characterization of the effects of phosphorylation by CK2 on the structure and binding properties of human HP1β.10

Citation

Dessen P

CBX1 (chromobox 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45621/js/lib/favicon/apple-touch-icon.png