GPR143 (G protein-coupled receptor 143)

2007-02-01  

Identity

HGNC
LOCATION
Xp22.2
LOCUSID
ALIAS
NYS6,OA1
FUSION GENES

Other Information

Locus ID:

NCBI: 4935
MIM: 300808
HGNC: 20145
Ensembl: ENSG00000101850

Variants:

dbSNP: 4935
ClinVar: 4935
TCGA: ENSG00000101850
COSMIC: GPR143

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101850ENST00000431126C9J9N1
ENSG00000101850ENST00000447366H7BZN6
ENSG00000101850ENST00000467482P51810

Expression (GTEx)

0
1
2
3
4
5
6
7

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Amine ligand-binding receptorsREACTOMER-HSA-375280

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
368009962023GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis.15
373946372023L-DOPA Receptor GPR143 Functionally Couples with Adrenergic α(1B) Receptor at the Second Transmembrane Interface.0
382224452023GPR143 mutations in an X-linked infantile nystagmus syndrome cohort in Southeast China.0
368009962023GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis.15
373946372023L-DOPA Receptor GPR143 Functionally Couples with Adrenergic α(1B) Receptor at the Second Transmembrane Interface.0
382224452023GPR143 mutations in an X-linked infantile nystagmus syndrome cohort in Southeast China.0
337850182021Identification of a novel GPR143 mutation in a large Chinese family with isolated foveal hypoplasia.2
343462692021GPR143 genotypic and ocular phenotypic characterisation in a Chinese cohort with ocular albinism.2
337850182021Identification of a novel GPR143 mutation in a large Chinese family with isolated foveal hypoplasia.2
343462692021GPR143 genotypic and ocular phenotypic characterisation in a Chinese cohort with ocular albinism.2
317464312020A novel GPR143 mutation in a Chinese family with X‑linked ocular albinism type 1.3
317464312020A novel GPR143 mutation in a Chinese family with X‑linked ocular albinism type 1.3
315742852019Evaluation of the iris thickness changes for the Chinese families with GPR143 gene mutations.2
318845822019GPR143 Signaling and Retinal Degeneration.6
315742852019Evaluation of the iris thickness changes for the Chinese families with GPR143 gene mutations.2

Citation

Dessen P

GPR143 (G protein-coupled receptor 143)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45630/cancer-prone-explorer/css/template-nav.css