ABCE1 (ATP binding cassette subfamily E member 1)

2007-02-01  

Identity

HGNC
LOCATION
4q31.21
LOCUSID
ALIAS
ABC38,OABP,RLI,RLI1,RNASEL1,RNASELI,RNS4I
FUSION GENES

Other Information

Locus ID:

NCBI: 6059
MIM: 601213
HGNC: 69
Ensembl: ENSG00000164163

Variants:

dbSNP: 6059
ClinVar: 6059
TCGA: ENSG00000164163
COSMIC: ABCE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164163ENST00000296577P61221
ENSG00000164163ENST00000502586D6RGF4
ENSG00000164163ENST00000504292H0Y990
ENSG00000164163ENST00000507193D6R9I9

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
ABC-family proteins mediated transportREACTOMER-HSA-382556

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
201224022010The role of ABCE1 in eukaryotic posttermination ribosomal recycling.136
214481322011Dissociation by Pelota, Hbs1 and ABCE1 of mammalian vacant 80S ribosomes and stalled elongation complexes.111
117801232002Identification of a host protein essential for assembly of immature HIV-1 capsids.83
117801232002Identification of a host protein essential for assembly of immature HIV-1 capsids.83
228513152012HIV-1 Gag co-opts a cellular complex containing DDX6, a helicase that facilitates capsid assembly.47
162756482006Basic residues in the nucleocapsid domain of Gag are required for interaction of HIV-1 gag with ABCE1 (HP68), a cellular protein important for HIV-1 capsid assembly.40
276814152016Dynamic Regulation of a Ribosome Rescue Pathway in Erythroid Cells and Platelets.37
172337572007Host ABCE1 is at plasma membrane HIV assembly sites and its dissociation from Gag is linked to subsequent events of virus production.29
147475302004Conservation of a stepwise, energy-sensitive pathway involving HP68 for assembly of primate lentivirus capsids in cells.26
147475302004Conservation of a stepwise, energy-sensitive pathway involving HP68 for assembly of primate lentivirus capsids in cells.26

Citation

Dessen P

ABCE1 (ATP binding cassette subfamily E member 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45805/abce1