THEMIS2 (thymocyte selection associated family member 2)

2007-02-01  

Identity

HGNC
LOCATION
1p35.3
LOCUSID
ALIAS
C1orf38,ICB-1,ICB1

Other Information

Locus ID:

NCBI: 9473
MIM: 617856
HGNC: 16839
Ensembl: ENSG00000130775

Variants:

dbSNP: 9473
ClinVar: 9473
TCGA: ENSG00000130775
COSMIC: THEMIS2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130775ENST00000328928Q5TEJ8
ENSG00000130775ENST00000373921Q5TEJ8
ENSG00000130775ENST00000373925Q5TEJ8
ENSG00000130775ENST00000373927Q5TEJ8
ENSG00000130775ENST00000427466Q5TEK2
ENSG00000130775ENST00000442118X6RK39
ENSG00000130775ENST00000456990H7C124

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
227325882012Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function.16
121915722002Detection of increased icb-1 transcript levels in maturing HL-60 cells: a novel marker for granulocytic and monocytic in vitro differentiation.6
162194722005Expression of icb-1 gene is interferon-gamma inducible in breast and ovarian cancer cell lines and affects the IFN gamma-response of SK-OV-3 ovarian cancer cells.4
193088122009Single nucleotide polymorphisms in human gene icb-1 and breast cancer susceptibility.2
193088122009Single nucleotide polymorphisms in human gene icb-1 and breast cancer susceptibility.2
234744912013icb-1 Gene counteracts growth of ovarian cancer cell lines.2
199427132010Knockdown of ICB-1 gene enhanced estrogen responsiveness of ovarian and breast cancer cells.1
214555652011Silencing of the icb-1 gene inhibits the induction of differentiation-associated genes by vitamin D3 and all-trans retinoic acid in gynecological cancer cells.1
205690722010Icb-1 Gene expression is elevated in human endometrial adenocarcinoma and is closely associated with HER2 expression.0

Citation

Dessen P

THEMIS2 (thymocyte selection associated family member 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46069/themis2