EN2 (engrailed homeobox 2)

2007-02-01  

Identity

HGNC
LOCATION
7q36.3
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 2020
MIM: 131310
HGNC: 3343
Ensembl: ENSG00000164778

Variants:

dbSNP: 2020
ClinVar: 2020
TCGA: ENSG00000164778
COSMIC: EN2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164778ENST00000297375P19622

Expression (GTEx)

0
10
20
30
40
50
60
70
80

References

Pubmed IDYearTitleCitations
150243962004Association of the homeobox transcription factor, ENGRAILED 2, 3, with autism spectrum disorder.71
162522432005Support for the homeobox transcription factor gene ENGRAILED 2 as an autism spectrum disorder susceptibility locus.61
172675602007Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1.40
213640372011Engrailed-2 (EN2): a tumor specific urinary biomarker for the early diagnosis of prostate cancer.34
252902672014Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum.30
196156702009Autism-associated haplotype affects the regulation of the homeobox gene, ENGRAILED 2.25
196156702009Autism-associated haplotype affects the regulation of the homeobox gene, ENGRAILED 2.25
179489012008Association of the ENGRAILED 2 (EN2) gene with autism in Chinese Han population.22
179489012008Association of the ENGRAILED 2 (EN2) gene with autism in Chinese Han population.22
160071492005EN2 is a candidate oncogene in human breast cancer.16

Citation

Dessen P

EN2 (engrailed homeobox 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46279/en2-(engrailed-homeobox-2)