NUDC (nuclear distribution C, dynein complex regulator)

2007-02-01  

Identity

HGNC
NUDC
LOCATION
1p36.11
LOCUSID
10726
ALIAS
HNUDC,MNUDC,NPD011
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10726
MIM: 610325
HGNC: 8045
Ensembl: ENSG00000090273

Variants:

dbSNP: 10726
ClinVar: 10726
TCGA: ENSG00000090273
COSMIC: NUDC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000090273ENST00000321265Q9Y266
ENSG00000090273ENST00000435827A0A0A0MSU9
ENSG00000090273ENST00000452707A0A0A0MSS4

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic PrometaphaseREACTOMER-HSA-68877
Resolution of Sister Chromatid CohesionREACTOMER-HSA-2500257
Mitotic Metaphase and AnaphaseREACTOMER-HSA-2555396
Mitotic AnaphaseREACTOMER-HSA-68882
Separation of Sister ChromatidsREACTOMER-HSA-2467813
Mitotic Telophase/CytokinesisREACTOMER-HSA-68884

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
350631332022NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems.16
350631332022NudC guides client transfer between the Hsp40/70 and Hsp90 chaperone systems.16
340603502021Transcriptome Analysis and the Prognostic Role of NUDC in Diffuse and Intestinal Gastric Cancer.3
340603502021Transcriptome Analysis and the Prognostic Role of NUDC in Diffuse and Intestinal Gastric Cancer.3
333744562020N-Acetyl-D-Glucosamine Kinase Interacts with NudC and Lis1 in Dynein Motor Complex and Promotes Cell Migration.6
333744562020N-Acetyl-D-Glucosamine Kinase Interacts with NudC and Lis1 in Dynein Motor Complex and Promotes Cell Migration.6
279594292017MicroRNA-194 suppresses prostate cancer migration and invasion by downregulating human nuclear distribution protein.8
279594292017MicroRNA-194 suppresses prostate cancer migration and invasion by downregulating human nuclear distribution protein.8
270357592016MicroRNA-194 restrains the cell progression of non-small cell lung cancer by targeting human nuclear distribution protein C.5
270740402016Dynamic Phosphorylation of NudC by Aurora B in Cytokinesis.4
270357592016MicroRNA-194 restrains the cell progression of non-small cell lung cancer by targeting human nuclear distribution protein C.5
270740402016Dynamic Phosphorylation of NudC by Aurora B in Cytokinesis.4
240692382013NudC deacetylation regulates mitotic progression.13
240692382013NudC deacetylation regulates mitotic progression.13
214731392011[Expression and clinical significance of human nuclear distribution C in nasopharyngeal carcinoma].0

Citation

Dessen P

NUDC (nuclear distribution C, dynein complex regulator)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46349/case-report-explorer/css/template-card.css