DPP3 (dipeptidyl peptidase 3)

2007-02-01  

Identity

HGNC
LOCATION
11q13.2
LOCUSID
ALIAS
DPPIII
FUSION GENES

Other Information

Locus ID:

NCBI: 10072
MIM: 606818
HGNC: 3008
Ensembl: ENSG00000254986

Variants:

dbSNP: 10072
ClinVar: 10072
TCGA: ENSG00000254986
COSMIC: DPP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000254986ENST00000526515E9PKK8
ENSG00000254986ENST00000530165Q9NY33
ENSG00000254986ENST00000531314E9PQF2
ENSG00000254986ENST00000531354E9PPK9
ENSG00000254986ENST00000531863G3V180
ENSG00000254986ENST00000532019E9PNX5
ENSG00000254986ENST00000532677G3V1D3
ENSG00000254986ENST00000533725E9PQ14
ENSG00000254986ENST00000541961Q9NY33

Expression (GTEx)

0
10
20
30
40
50
60

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
233820442013Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination.64
224932382012Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III.12
273157862016Identification of dipeptidyl peptidase 3 as the Angiotensin-(1-7) degrading peptidase in human HK-2 renal epithelial cells.9
145296812003Tumor cytosol dipeptidyl peptidase III activity is increased with histological aggressiveness of ovarian primary carcinomas.8
181638852008Functional tyrosine residue in the active center of human dipeptidyl peptidase III.5
202363182010Ets-1/Elk-1 is a critical mediator of dipeptidyl-peptidase III transcription in human glioblastoma cells.5
270251542016Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition.5
233621972013Hydrolysis of dipeptide derivatives reveals the diversity in the M49 family.3
236679072012Molecular determinants of human dipeptidyl peptidase III sensitivity to thiol modifying reagents.3
263345752015Molecular simulations reveal that the long range fluctuations of human DPP III change upon ligand binding.3

Citation

Dessen P

DPP3 (dipeptidyl peptidase 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46396/dpp3-(dipeptidyl-peptidase-3)