NOCT (nocturnin)

2007-02-01  

Identity

HGNC
NOCT
LOCATION
4q31.1
LOCUSID
25819
ALIAS
CCR4L,CCRN4L,Ccr4c,NOC
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 25819
MIM: 608468
HGNC: 14254
Ensembl: ENSG00000151014

Variants:

dbSNP: 25819
ClinVar: 25819
TCGA: ENSG00000151014
COSMIC: NOCT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000151014ENST00000280614Q9UK39
ENSG00000151014ENST00000630479Q8WTX0

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Circadian ClockREACTOMER-HSA-400253
BMAL1:CLOCK,NPAS2 activates circadian gene expressionREACTOMER-HSA-1368108

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
328392742020Differential processing and localization of human Nocturnin controls metabolism of mRNA and nicotinamide adenine dinucleotide cofactors.7
328392742020Differential processing and localization of human Nocturnin controls metabolism of mRNA and nicotinamide adenine dinucleotide cofactors.7
314679102019NOCTURNIN Gene Diurnal Variation in Healthy Volunteers and Expression Levels in Shift Workers.8
314679102019NOCTURNIN Gene Diurnal Variation in Healthy Volunteers and Expression Levels in Shift Workers.8
298603382018The structure of human Nocturnin reveals a conserved ribonuclease domain that represses target transcript translation and abundance in cells.16
302576002018Regulatory roles of vertebrate Nocturnin: insights and remaining mysteries.5
303899762018Crystal Structure of Human Nocturnin Catalytic Domain.9
298603382018The structure of human Nocturnin reveals a conserved ribonuclease domain that represses target transcript translation and abundance in cells.16
302576002018Regulatory roles of vertebrate Nocturnin: insights and remaining mysteries.5
303899762018Crystal Structure of Human Nocturnin Catalytic Domain.9
265416752015Poly(A)-specific ribonuclease and Nocturnin in squamous cell lung cancer: prognostic value and impact on gene expression.20
265416752015Poly(A)-specific ribonuclease and Nocturnin in squamous cell lung cancer: prognostic value and impact on gene expression.20
248216102014Association between CLOCK, PER3 and CCRN4L with non‑small cell lung cancer in Brazilian patients.18
248216102014Association between CLOCK, PER3 and CCRN4L with non‑small cell lung cancer in Brazilian patients.18
239227592013Genetic variation in the NOC gene is associated with body mass index in Chinese subjects.7

Citation

Dessen P

NOCT (nocturnin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46547/img/js/lib/jquery-3.5.1.min.js