POU2F2 (POU class 2 homeobox 2)

2007-02-01  

Identity

HGNC
POU2F2
LOCATION
19q13.2
LOCUSID
5452
ALIAS
OCT2,OTF2,Oct-2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5452
MIM: 164176
HGNC: 9213
Ensembl: ENSG00000028277

Variants:

dbSNP: 5452
ClinVar: 5452
TCGA: ENSG00000028277
COSMIC: POU2F2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000028277ENST00000342301B5ME60
ENSG00000028277ENST00000389341P09086
ENSG00000028277ENST00000524801A0A1B0GV81
ENSG00000028277ENST00000526816P09086
ENSG00000028277ENST00000526831U3KQN1
ENSG00000028277ENST00000528894U3KQ96
ENSG00000028277ENST00000529067P09086
ENSG00000028277ENST00000529952P09086
ENSG00000028277ENST00000532176A0A1B0GW97
ENSG00000028277ENST00000533548H0YNG1
ENSG00000028277ENST00000534559E9PR37
ENSG00000028277ENST00000560398H0YLL6
ENSG00000028277ENST00000560558H0YNW1
ENSG00000028277ENST00000560804H0YKT2
ENSG00000028277ENST00000598842M0R1I6
ENSG00000028277ENST00000625670A0A0D9SF23
ENSG00000028277ENST00000636631A0A1B0GUT9

Expression (GTEx)

0
10
20
30
40
50
60
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
RNA polymerase II transcribes snRNA genesREACTOMER-HSA-6807505

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382547232024Transcriptional Coactivator BOB1 (OBF1, OCA-B) Modulates the Specificity of DNA Recognition by the POU-Domain Factors OCT1 and OCT2 in a Monomeric Configuration.0
383188532024POU2F2-mediated upregulation of lncRNA PTPRG-AS1 inhibits ferroptosis in breast cancer via miR-376c-3p/SLC7A11 axis.0
382547232024Transcriptional Coactivator BOB1 (OBF1, OCA-B) Modulates the Specificity of DNA Recognition by the POU-Domain Factors OCT1 and OCT2 in a Monomeric Configuration.0
383188532024POU2F2-mediated upregulation of lncRNA PTPRG-AS1 inhibits ferroptosis in breast cancer via miR-376c-3p/SLC7A11 axis.0
367548972023OCT2 expression in histiocytoses.1
368495102023The MYC-regulated lncRNA LNROP (ENSG00000254887) enables MYC-driven cell proliferation by controlling the expression of OCT2.2
367548972023OCT2 expression in histiocytoses.1
368495102023The MYC-regulated lncRNA LNROP (ENSG00000254887) enables MYC-driven cell proliferation by controlling the expression of OCT2.2
355264832022CBX7 represses the POU2F2 to inhibit the PD-L1 expression and regulate the immune response in bladder cancer.2
355264832022CBX7 represses the POU2F2 to inhibit the PD-L1 expression and regulate the immune response in bladder cancer.2
335124662021OBF1 and Oct factors control the germinal center transcriptional program.11
338324812021POU2F2 promotes the proliferation and motility of lung cancer cells by activating AGO1.6
339315892021POU2F2 regulates glycolytic reprogramming and glioblastoma progression via PDPK1-dependent activation of PI3K/AKT/mTOR pathway.22
339659582021Long Non-Coding RNA ARAP1-AS1 Facilitates the Progression of Cervical Cancer by Regulating miR-149-3p and POU2F2.7
335124662021OBF1 and Oct factors control the germinal center transcriptional program.11

Citation

Dessen P

POU2F2 (POU class 2 homeobox 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46573/css/lib/css/lib/dataTables.bootstrap.min.css