HOXB13 (homeobox B13)

2007-02-01  

Identity

HGNC
LOCATION
17q21.32
LOCUSID
ALIAS
HPC9,PSGD
FUSION GENES

Other Information

Locus ID:

NCBI: 10481
MIM: 604607
HGNC: 5112
Ensembl: ENSG00000159184

Variants:

dbSNP: 10481
ClinVar: 10481
TCGA: ENSG00000159184
COSMIC: HOXB13

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000159184ENST00000290295Q92826

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
222362242012Germline mutations in HOXB13 and prostate-cancer risk.178
264576462015The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis.95
199172492009The homeodomain protein HOXB13 regulates the cellular response to androgens.83
279564982017H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal squamous cell carcinoma.72
171458632006Epigenetic silencing of novel tumor suppressors in malignant melanoma.71
243902822014A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding.63
230648732013HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG).61
170087032006The HOXB13:IL17BR expression index is a prognostic factor in early-stage breast cancer.60
156042912004HOXB13 induces growth suppression of prostate cancer cells as a repressor of hormone-activated androgen receptor signaling.56
179426762007HOXB13 promotes ovarian cancer progression.45

Citation

Dessen P

HOXB13 (homeobox B13)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46597/hoxb13