CCNB3 (cyclin B3)

2007-04-01  

Identity

HGNC
LOCATION
Xp11.22
LOCUSID
ALIAS
CYCB3
FUSION GENES

Other Information

Locus ID:

NCBI: 85417
MIM: 300456
HGNC: 18709
Ensembl: ENSG00000147082

Variants:

dbSNP: 85417
ClinVar: 85417
TCGA: ENSG00000147082
COSMIC: CCNB3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147082ENST00000276014Q8WWL7
ENSG00000147082ENST00000348603Q8WWL7
ENSG00000147082ENST00000376038Q8WWL7
ENSG00000147082ENST00000376042Q8WWL7
ENSG00000147082ENST00000476167Q8WWL7

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Cell cycleKEGGko04110
p53 signaling pathwayKEGGko04115
Progesterone-mediated oocyte maturationKEGGko04914
Cell cycleKEGGhsa04110
p53 signaling pathwayKEGGhsa04115
Progesterone-mediated oocyte maturationKEGGhsa04914
FoxO signaling pathwayKEGGhsa04068
Cell cycle - G2/M transitionKEGGhsa_M00693
Cell cycle - G2/M transitionKEGGM00693

References

Pubmed IDYearTitleCitations
223879972012A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion.77
121850762002Characterization and expression of mammalian cyclin b3, a prepachytene meiotic cyclin.50
248058592014BCOR-CCNB3 (Ewing-like) sarcoma: a clinicopathologic analysis of 10 cases, in comparison with conventional Ewing sarcoma.21
253605852015BCOR-CCNB3 fusions are frequent in undifferentiated sarcomas of male children.20
288174042017Primary Renal Sarcomas With BCOR-CCNB3 Gene Fusion: A Report of 2 Cases Showing Histologic Overlap With Clear Cell Sarcoma of Kidney, Suggesting Further Link Between BCOR-related Sarcomas of the Kidney and Soft Tissues.10
288770602017Clinicopathologic Diversity of Undifferentiated Sarcoma With BCOR-CCNB3 Fusion: Analysis of 11 Cases With a Reappraisal of the Utility of Immunohistochemistry for BCOR and CCNB3.4
260371542015Screening of BCOR-CCNB3 sarcoma using immunohistochemistry for CCNB3: A clinicopathological report of three pediatric cases.3
214044612011Proteomic identification of overexpressed adenomatous polyposis coli and cyclin B3 during endoderm differentiation from human embryonic stem cells.1
300642352018An undifferentiated sarcoma with BCOR-CCNB3 fusion transcript - pathological and clinical retrospective study.1
318763612020BCOR-CCNB3 fusion-positive clear cell sarcoma of the kidney.0

Citation

Dessen P

CCNB3 (cyclin B3)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46654/ccnb3