ELF5 (E74 like ETS transcription factor 5)

2007-04-01  

Identity

HGNC
ELF5
LOCATION
11p13
LOCUSID
2001
ALIAS
ESE2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2001
MIM: 605169
HGNC: 3320
Ensembl: ENSG00000135374

Variants:

dbSNP: 2001
ClinVar: 2001
TCGA: ENSG00000135374
COSMIC: ELF5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000135374ENST00000257832Q9UKW6
ENSG00000135374ENST00000257832A8K443
ENSG00000135374ENST00000312319Q9UKW6
ENSG00000135374ENST00000429939Q9UKW6
ENSG00000135374ENST00000532417Q9UKW6
ENSG00000135374ENST00000620316A0A087X1W9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Prolactin signaling pathwayKEGGhsa04917
Prolactin signaling pathwayKEGGko04917

References

Pubmed IDYearTitleCitations
359708492022ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19.6
359708492022ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19.6
341403482021Breast-Specific Molecular Clocks Comprised of ELF5 Expression and Promoter Methylation Identify Individuals Susceptible to Cancer Initiation.8
341461972021ELF5 inhibits the proliferation and invasion of breast cancer cells by regulating CD24.9
341403482021Breast-Specific Molecular Clocks Comprised of ELF5 Expression and Promoter Methylation Identify Individuals Susceptible to Cancer Initiation.8
341461972021ELF5 inhibits the proliferation and invasion of breast cancer cells by regulating CD24.9
318959442020ELF5 modulates the estrogen receptor cistrome in breast cancer.9
320961742020WWOX regulates the Elf5/Snail1 pathway to affect epithelial-mesenchymal transition of ovarian carcinoma cells in vitro.2
322845422020Loss of ELF5-FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling.43
318959442020ELF5 modulates the estrogen receptor cistrome in breast cancer.9
320961742020WWOX regulates the Elf5/Snail1 pathway to affect epithelial-mesenchymal transition of ovarian carcinoma cells in vitro.2
322845422020Loss of ELF5-FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling.43
306968032019Overexpression of E74-Like Factor 5 (ELF5) Inhibits Migration and Invasion of Ovarian Cancer Cells.7
315574072019Coordinate regulation of ELF5 and EHF at the chr11p13 CF modifier region.10
306968032019Overexpression of E74-Like Factor 5 (ELF5) Inhibits Migration and Invasion of Ovarian Cancer Cells.7

Citation

Dessen P

ELF5 (E74 like ETS transcription factor 5)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46669/gene-fusions/favicon/apple-touch-icon.png