FRMD4A (FERM domain containing 4A)

2007-04-01  

Identity

HGNC
FRMD4A
LOCATION
10p13
LOCUSID
55691
ALIAS
CCAFCA,FRMD4,bA295P9.4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55691
MIM: 616305
HGNC: 25491
Ensembl: ENSG00000151474

Variants:

dbSNP: 55691
ClinVar: 55691
TCGA: ENSG00000151474
COSMIC: FRMD4A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000151474ENST00000264546Q5T376
ENSG00000151474ENST00000357447Q9P2Q2
ENSG00000151474ENST00000475141S4R324
ENSG00000151474ENST00000477221A0A0J9YXB2
ENSG00000151474ENST00000493380S4R3Y6
ENSG00000151474ENST00000495956A0A0J9YYA7
ENSG00000151474ENST00000632570A0A0J9YWI3
ENSG00000151474ENST00000640906A0A1W2PQE7
ENSG00000151474ENST00000648400A0A3B3ISM9
ENSG00000151474ENST00000648761A0A3B3IRJ0
ENSG00000151474ENST00000649099A0A3B3ISM9
ENSG00000151474ENST00000649155A0A3B3ISM9
ENSG00000151474ENST00000649246A0A3B3ISM9
ENSG00000151474ENST00000649423A0A3B3IS86
ENSG00000151474ENST00000649947A0A3B3ISM0
ENSG00000151474ENST00000650014A0A3B3ISR1
ENSG00000151474ENST00000650137A0A3B3ISB3

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
353125142022Polymorphisms in the FRMD4A Gene Are Associated With Chronic Obstructive Pulmonary Disease Susceptibility in a Latin American Population.2
353125142022Polymorphisms in the FRMD4A Gene Are Associated With Chronic Obstructive Pulmonary Disease Susceptibility in a Latin American Population.2
270447542016FRMD4A-cytohesin signaling modulates the cellular release of tau.23
276663462016FRMD4A: A potential therapeutic target for the treatment of tongue squamous cell carcinoma.6
270447542016FRMD4A-cytohesin signaling modulates the cellular release of tau.23
276663462016FRMD4A: A potential therapeutic target for the treatment of tongue squamous cell carcinoma.6
253880052015A syndrome of congenital microcephaly, intellectual disability and dysmorphism with a homozygous mutation in FRMD4A.13
253880052015A syndrome of congenital microcephaly, intellectual disability and dysmorphism with a homozygous mutation in FRMD4A.13
224306742013Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease.49
224306742013Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease.49
220062182012Large-scale genome-wide association study of Asian population reveals genetic factors in FRMD4A and other loci influencing smoking initiation and nicotine dependence.37
225645252012FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis.25
220062182012Large-scale genome-wide association study of Asian population reveals genetic factors in FRMD4A and other loci influencing smoking initiation and nicotine dependence.37
225645252012FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis.25
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

FRMD4A (FERM domain containing 4A)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46677/css/favicon/js/web-card-_common.js