RNF20 (ring finger protein 20)

2007-04-01  

Identity

HGNC
RNF20
LOCATION
9q31.1
LOCUSID
56254
ALIAS
BRE1,BRE1A,hBRE1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 56254
MIM: 607699
HGNC: 10062
Ensembl: ENSG00000155827

Variants:

dbSNP: 56254
ClinVar: 56254
TCGA: ENSG00000155827
COSMIC: RNF20

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000155827ENST00000374819C9JXC9
ENSG00000155827ENST00000389120Q5VTR2
ENSG00000155827ENST00000466817C9J0A5
ENSG00000155827ENST00000479306C9JWJ4

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Protein ubiquitinationREACTOMER-HSA-8852135
E3 ubiquitin ligases ubiquitinate target proteinsREACTOMER-HSA-8866654

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382403472024RNF20 Regulates Oocyte Meiotic Spindle Assembly by Recruiting TPM3 to Centromeres and Spindle Poles.1
383158422024RNF20 contributes to epigenetic immunosuppression through CDK9-dependent LSD1 stabilization.1
385178922024Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes.0
385195112024Structure of the human Bre1 complex bound to the nucleosome.0
386081462024RNF20 Reduces Cell Proliferation and Warburg Effect by Promoting NLRP3 Ubiquitination in Liver Cancer.0
382403472024RNF20 Regulates Oocyte Meiotic Spindle Assembly by Recruiting TPM3 to Centromeres and Spindle Poles.1
383158422024RNF20 contributes to epigenetic immunosuppression through CDK9-dependent LSD1 stabilization.1
385178922024Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes.0
385195112024Structure of the human Bre1 complex bound to the nucleosome.0
386081462024RNF20 Reduces Cell Proliferation and Warburg Effect by Promoting NLRP3 Ubiquitination in Liver Cancer.0
366509382023RNF20 deletion causes inflammation in model of sepsis through the NLRP3 activation.2
371558762023The RPA-RNF20-SNF2H cascade promotes proper chromosome segregation and homologous recombination repair.3
379763592023Iron deficiency-induced ferritinophagy impairs skeletal muscle regeneration through RNF20-mediated H2Bub1 modification.0
366509382023RNF20 deletion causes inflammation in model of sepsis through the NLRP3 activation.2
371558762023The RPA-RNF20-SNF2H cascade promotes proper chromosome segregation and homologous recombination repair.3

Citation

Dessen P

RNF20 (ring finger protein 20)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46758/haematological-explorer/img/logo-atlas-4.svg