STAU1 (staufen double-stranded RNA binding protein 1)

2007-04-01  

Identity

HGNC
LOCATION
20q13.13
LOCUSID
ALIAS
PPP1R150,STAU
FUSION GENES

Other Information

Locus ID:

NCBI: 6780
MIM: 601716
HGNC: 11370
Ensembl: ENSG00000124214

Variants:

dbSNP: 6780
ClinVar: 6780
TCGA: ENSG00000124214
COSMIC: STAU1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124214ENST00000340954O95793
ENSG00000124214ENST00000347458O95793
ENSG00000124214ENST00000360426O95793
ENSG00000124214ENST00000371792Q5JW30
ENSG00000124214ENST00000371802O95793
ENSG00000124214ENST00000371828O95793
ENSG00000124214ENST00000371856O95793
ENSG00000124214ENST00000437404Q5JW28
ENSG00000124214ENST00000456866F6UDC6
ENSG00000124214ENST00000614381A0A087X1A5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
213079422011lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements.460
175106342007Staufen1 regulates diverse classes of mammalian transcripts.90
257999842015hiCLIP reveals the in vivo atlas of mRNA secondary structures recognized by Staufen 1.80
150240552004Identification of Staufen in the human immunodeficiency virus type 1 Gag ribonucleoprotein complex and a role in generating infectious viral particles.60
151218982004The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs.60
280047502016SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization.60
200536372010Novel Staufen1 ribonucleoproteins prevent formation of stress granules but favour encapsidation of HIV-1 genomic RNA.55
180941222008A genome-wide approach identifies distinct but overlapping subsets of cellular mRNAs associated with Staufen1- and Staufen2-containing ribonucleoprotein complexes.53
224317502012The RNA-binding protein Staufen1 is increased in DM1 skeletal muscle and promotes alternative pre-mRNA splicing.48
238245402013STAU1 binding 3' UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown.48

Citation

Dessen P

STAU1 (staufen double-stranded RNA binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46907/stau1