PPP1R1C (protein phosphatase 1 regulatory inhibitor subunit 1C)

2007-04-01 Affiliation

Identity

HGNC

PPP1R1C

LOCATION

2q31.3

LOCUSID

151242

ALIAS

IPP5

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 151242
MIM: 613240
HGNC: 14940
Ensembl: ENSG00000150722

Variants:

dbSNP: 151242
ClinVar: 151242
TCGA: ENSG00000150722
COSMIC: PPP1R1C

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000150722	ENST00000280295	Q8WVI7
ENSG00000150722	ENST00000409137	Q8WVI7
ENSG00000150722	ENST00000409702	Q8WVI7

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	62
20468071	2010	Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.	17
19874272	2009	Effect of IPP5, a novel inhibitor of PP1, on apoptosis and the underlying mechanisms involved.	2
24935604	2014	8-60hIPP5(m)-induced G2/M cell cycle arrest involves activation of ATM/p53/p21(cip1/waf1) pathways and delayed cyclin B1 nuclear translocation.	2
22939397	2012	IPP5, a novel inhibitor of protein phosphatase 1, suppresses tumor growth and progression of cervical carcinoma cells by inducing G2/M arrest.	1
25339026	2014	Sensitization of cervical carcinoma cells to paclitaxel by an IPP5 active mutant.	1

Citation

Dessen P

PPP1R1C (protein phosphatase 1 regulatory inhibitor subunit 1C)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47023/ppp1r1c