NKRF (NFKB repressing factor)

2007-04-01  

Identity

HGNC
NKRF
LOCATION
Xq24
LOCUSID
55922
ALIAS
ITBA4,NRF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55922
MIM: 300440
HGNC: 19374
Ensembl: ENSG00000186416

Variants:

dbSNP: 55922
ClinVar: 55922
TCGA: ENSG00000186416
COSMIC: NKRF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000186416ENST00000304449O15226
ENSG00000186416ENST00000304449A3F769
ENSG00000186416ENST00000371527O15226
ENSG00000186416ENST00000371527A3F769
ENSG00000186416ENST00000542113O15226

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
379212192024WWP2 binds to NKRF, enhances the NF-κB signaling, and promotes malignant phenotypes of acute myeloid leukemia cells.0
386123872024A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-β Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells.0
379212192024WWP2 binds to NKRF, enhances the NF-κB signaling, and promotes malignant phenotypes of acute myeloid leukemia cells.0
386123872024A1CF Binding to the p65 Interaction Site on NKRF Decreased IFN-β Expression and p65 Phosphorylation (Ser536) in Renal Carcinoma Cells.0
321796862020Structural basis for DEAH-helicase activation by G-patch proteins.32
324680202020Upregulation of miRNA‑301a‑3p promotes tumor progression in gastric cancer by suppressing NKRF and activating NF‑κB signaling.8
321796862020Structural basis for DEAH-helicase activation by G-patch proteins.32
324680202020Upregulation of miRNA‑301a‑3p promotes tumor progression in gastric cancer by suppressing NKRF and activating NF‑κB signaling.8
307296762019MiR-802 causes nephropathy by suppressing NF-κB-repressing factor in obese mice and human.18
307296762019MiR-802 causes nephropathy by suppressing NF-κB-repressing factor in obese mice and human.18
280963322017Human NF-κB repressing factor acts as a stress-regulated switch for ribosomal RNA processing and nucleolar homeostasis surveillance.18
281156242017The G-patch protein NF-κB-repressing factor mediates the recruitment of the exonuclease XRN2 and activation of the RNA helicase DHX15 in human ribosome biogenesis.44
292618072017Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein.9
280963322017Human NF-κB repressing factor acts as a stress-regulated switch for ribosomal RNA processing and nucleolar homeostasis surveillance.18
281156242017The G-patch protein NF-κB-repressing factor mediates the recruitment of the exonuclease XRN2 and activation of the RNA helicase DHX15 in human ribosome biogenesis.44

Citation

Dessen P

NKRF (NFKB repressing factor)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47066/img/css/favicon/favicon-32x32.png