ACYP2 (acylphosphatase 2)

2007-04-01  

Identity

HGNC
ACYP2
LOCATION
2p16.2
LOCUSID
98
ALIAS
ACYM,ACYP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 98
MIM: 102595
HGNC: 180
Ensembl: ENSG00000170634

Variants:

dbSNP: 98
ClinVar: 98
TCGA: ENSG00000170634
COSMIC: ACYP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170634ENST00000303536F8WA34
ENSG00000170634ENST00000394666P14621
ENSG00000170634ENST00000394666A0A140VJD7
ENSG00000170634ENST00000406041E9PF46
ENSG00000170634ENST00000422521U3KQ94
ENSG00000170634ENST00000494922U3KPX1
ENSG00000170634ENST00000606082U3KQ09
ENSG00000170634ENST00000606865U3KPX8
ENSG00000170634ENST00000607452U3KQL2

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Pyruvate metabolismKEGGko00620
Pyruvate metabolismKEGGhsa00620

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA162263534OtotoxicityDiseaseClinicalAnnotationassociatedPD26928270, 31666714
PA443557Brain NeoplasmsDiseaseClinicalAnnotationassociatedPD26928270, 31666714
PA443840DeafnessDiseaseClinicalAnnotationassociatedPD26928270, 31666714
PA449014cisplatinChemicalClinicalAnnotationassociatedPD26928270, 31666714

References

Pubmed IDYearTitleCitations
386152712024Study of the effect of ACYP2 single nucleotide polymorphisms rs843711 and rs843706 in Egyptian patients with hepatocellular carcinoma.0
386152712024Study of the effect of ACYP2 single nucleotide polymorphisms rs843711 and rs843706 in Egyptian patients with hepatocellular carcinoma.0
329371842021The influence of TERC, TERT and ACYP2 genes polymorphisms on plasma telomerase concentration, telomeres length and T2DM.4
339212542021Telomere Length and Male Fertility.12
329371842021The influence of TERC, TERT and ACYP2 genes polymorphisms on plasma telomerase concentration, telomeres length and T2DM.4
339212542021Telomere Length and Male Fertility.12
325177172020ACYP2 contributes to malignant progression of glioma through promoting Ca(2+) efflux and subsequently activating c-Myc and STAT3 signals.4
325177172020ACYP2 contributes to malignant progression of glioma through promoting Ca(2+) efflux and subsequently activating c-Myc and STAT3 signals.4
303052942019Genetic and Modifiable Risk Factors Contributing to Cisplatin-induced Toxicities.31
310700192019The influence of ACYP2 polymorphisms on gastrointestinal cancer susceptibility in the Chinese Han population.2
311243132019Associations between polymorphisms of the ACYP2 gene and Liver cancer risk: A case-control study and meta-analysis.3
311407422019Assessment of the association between ACYP2 and laryngeal squamous cell carcinoma risk in Chinese males.1
312916402019Association between the ACYP2 Polymorphisms and IgAN Risk in the Chinese Han Population.0
314871242019Association between ACYP2 polymorphisms and the risk of renal cell cancer.2
303052942019Genetic and Modifiable Risk Factors Contributing to Cisplatin-induced Toxicities.31

Citation

Dessen P

ACYP2 (acylphosphatase 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47264/cancer-prone-explorer/js/lib/all.min.js