CNP (2,3-cyclic nucleotide 3 phosphodiesterase)

2007-04-01  

Identity

HGNC
CNP
LOCATION
17q21.2
LOCUSID
1267
ALIAS
CNP1,HLD20
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1267
MIM: 123830
HGNC: 2158
Ensembl: ENSG00000173786

Variants:

dbSNP: 1267
ClinVar: 1267
TCGA: ENSG00000173786
COSMIC: CNP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000173786ENST00000393888P09543
ENSG00000173786ENST00000393888A0A024R1T5
ENSG00000173786ENST00000393892P09543
ENSG00000173786ENST00000441615C9K0L8
ENSG00000173786ENST00000472031K7EQ27
ENSG00000173786ENST00000585452K7ERZ0
ENSG00000173786ENST00000587679K7ERC4
ENSG00000173786ENST00000589772K7EN66

Expression (GTEx)

0
100
200
300
400
500
600
700
800
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
bone marrow

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
191655272009Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.56
168914212006Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia.47
161032312005Process outgrowth in oligodendrocytes is mediated by CNP, a novel microtubule assembly myelin protein.45
179641172008Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia.41
190343802009Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis.36
163891932006Convergent evidence for 2',3'-cyclic nucleotide 3'-phosphodiesterase as a possible susceptibility gene for schizophrenia.35
163891932006Convergent evidence for 2',3'-cyclic nucleotide 3'-phosphodiesterase as a possible susceptibility gene for schizophrenia.35
230849242012Inhibition of HIV-1 particle assembly by 2',3'-cyclic-nucleotide 3'-phosphodiesterase.32
224738742012A myelin gene causative of a catatonia-depression syndrome upon aging.23

Citation

Dessen P

CNP (2,3-cyclic nucleotide 3 phosphodiesterase)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47306/cnp