OLIG1 (oligodendrocyte transcription factor 1)

2007-11-01  

Identity

HGNC
LOCATION
21q22.11
LOCUSID
ALIAS
BHLHB6,BHLHE21

Other Information

Locus ID:

NCBI: 116448
MIM: 606385
HGNC: 16983
Ensembl: ENSG00000184221

Variants:

dbSNP: 116448
ClinVar: 116448
TCGA: ENSG00000184221
COSMIC: OLIG1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184221ENST00000382348Q8TAK6
ENSG00000184221ENST00000426947H7C404

Expression (GTEx)

0
50
100
150
200
250
300

References

Pubmed IDYearTitleCitations
231652592012Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2.61
162672132005Olig transcription factors are expressed in oligodendrocyte and neuronal cells in human fetal CNS.46
172832882007A genetic family-based association study of OLIG2 in obsessive-compulsive disorder.24
259300752015Oligodendrocyte morphometry and expression of myelin - Related mRNA in ventral prefrontal white matter in major depressive disorder.21
214460392011Olig1 is expressed in human oligodendrocytes during maturation and regeneration.17
212067542010A systematic enhancer screen using lentivector transgenesis identifies conserved and non-conserved functional elements at the Olig1 and Olig2 locus.14
176908402008Expression of oligodendroglial differentiation markers in pilocytic astrocytomas identifies two clinical subsets and shows a significant correlation with proliferation index and progression free survival.13
173886692007Aberrant DNA methylation of OLIG1, a novel prognostic factor in non-small cell lung cancer.12
237207582013Oligodendrocyte transcription factor 1 (Olig1) is a Smad cofactor involved in cell motility induced by transforming growth factor-β.10
282535502017Olig1 is required for noggin-induced neonatal myelin repair.5

Citation

Dessen P

OLIG1 (oligodendrocyte transcription factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-11-01

Online version: http://atlasgeneticsoncology.org/gene/49814/olig1