GTF2E1 (general transcription factor IIE subunit 1)

2007-02-01  

Identity

HGNC
LOCATION
3q13.33
LOCUSID
ALIAS
FE,TF2E1,TFIIE-A
FUSION GENES

Other Information

Locus ID:

NCBI: 2960
MIM: 189962
HGNC: 4650
Ensembl: ENSG00000153767

Variants:

dbSNP: 2960
ClinVar: 2960
TCGA: ENSG00000153767
COSMIC: GTF2E1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000153767ENST00000283875P29083
ENSG00000153767ENST00000469772C9IYL4
ENSG00000153767ENST00000484715C9J329
ENSG00000153767ENST00000492959E9PER7

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Basal transcription factorsKEGGko03022
Basal transcription factorsKEGGhsa03022
Epstein-Barr virus infectionKEGGhsa05169
Epstein-Barr virus infectionKEGGko05169
Viral carcinogenesisKEGGhsa05203
Viral carcinogenesisKEGGko05203
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
HIV InfectionREACTOMER-HSA-162906
HIV Life CycleREACTOMER-HSA-162587
Late Phase of HIV Life CycleREACTOMER-HSA-162599
Transcription of the HIV genomeREACTOMER-HSA-167172
HIV Transcription InitiationREACTOMER-HSA-167161
RNA Polymerase II HIV Promoter EscapeREACTOMER-HSA-167162
Gene ExpressionREACTOMER-HSA-74160
RNA Polymerase II TranscriptionREACTOMER-HSA-73857
RNA Polymerase II Pre-transcription EventsREACTOMER-HSA-674695
RNA Polymerase II Transcription Pre-Initiation And Promoter OpeningREACTOMER-HSA-73779
RNA Polymerase II Transcription Initiation And Promoter ClearanceREACTOMER-HSA-76042
RNA Polymerase II Transcription InitiationREACTOMER-HSA-75953
RNA Polymerase II Promoter EscapeREACTOMER-HSA-73776
RNA polymerase II transcribes snRNA genesREACTOMER-HSA-6807505

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
183545012008Structural insight into the TFIIE-TFIIH interaction: TFIIE and p53 share the binding region on TFIIH.24
181605372008p53 and TFIIEalpha share a common binding site on the Tfb1/p62 subunit of TFIIH.21
153855562004A novel zinc finger structure in the large subunit of human general transcription factor TFIIE.16
165474622006Structure and oligomeric state of human transcription factor TFIIE.12
189508452009Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study.5
276394362016Crystal Structure of Human General Transcription Factor TFIIE at Atomic Resolution.5
254926092015Association of the winged helix motif of the TFIIEα subunit of TFIIE with either the TFIIEβ subunit or TFIIB distinguishes its functions in transcription.2
276027232016Dynamics of the Extended String-Like Interaction of TFIIE with the p62 Subunit of TFIIH.1
315290522019The hRPC62 subunit of human RNA polymerase III displays helicase activity.1

Citation

Dessen P

GTF2E1 (general transcription factor IIE subunit 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/50013/gtf2e1