ZMIZ1 (zinc finger MIZ-type containing 1)

2008-07-01  

Identity

HGNC
LOCATION
10q22.3
LOCUSID
ALIAS
MIZ,NEDDFSA,RAI17,TRAFIP10,ZIMP10
FUSION GENES

Other Information

Locus ID:

NCBI: 57178
MIM: 607159
HGNC: 16493
Ensembl: ENSG00000108175

Variants:

dbSNP: 57178
ClinVar: 57178
TCGA: ENSG00000108175
COSMIC: ZMIZ1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000108175ENST00000334512Q9ULJ6
ENSG00000108175ENST00000446377F6WR09
ENSG00000108175ENST00000611351A0A087WYE6

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
198791942009Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score.80
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.69
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
266248922015Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors.61
167778502006The novel PIAS-like protein hZimp10 enhances Smad transcriptional activity.21
199299862009Genome-wide SNP genotyping study using pooled DNA to identify candidate markers mediating susceptibility to end-stage renal disease attributed to Type 1 diabetes.21
175847852007The novel PIAS-like protein hZimp10 is a transcriptional co-activator of the p53 tumor suppressor.20
231614892013Convergence of the ZMIZ1 and NOTCH1 pathways at C-MYC in acute T lymphoblastic leukemias.20
179678852008The PIAS-like protein Zimp10 is essential for embryonic viability and proper vascular development.14
180075762008Fusion of ZMIZ1 to ABL1 in a B-cell acute lymphoblastic leukaemia with a t(9;10)(q34;q22.3) translocation.10

Citation

Dessen P

ZMIZ1 (zinc finger MIZ-type containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50211/zmiz1-(zinc-finger-miz-type-containing-1)