MIR215 (microRNA 215)

2009-01-01  

Identity

HGNC
LOCATION
1q41
LOCUSID
ALIAS
MIRN215,miRNA215,mir-215

Other Information

Locus ID:

NCBI: 406997
MIM: 610943
HGNC: 31592
Ensembl: ENSG00000207590
miRBase:

Variants:

dbSNP: 406997
ClinVar: 406997
TCGA: ENSG00000207590
COSMIC: MIR215

RNA/Proteins

Pathways

PathwaySourceExternal ID
MicroRNAs in cancerKEGGhsa05206
MicroRNAs in cancerKEGGko05206

References

Pubmed IDYearTitleCitations
209519462010Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development.182
190748762008Coordinated regulation of cell cycle transcripts by p53-Inducible microRNAs, miR-192 and miR-215.139
204337422010Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells.84
206473412010miR-192/miR-215 influence 5-fluorouracil resistance through cell cycle-mediated mechanisms complementary to its post-transcriptional thymidilate synthase regulation.55
211196042011MicroRNA-192 and -215 are upregulated in human gastric cancer in vivo and suppress ALCAM expression in vitro.45
257755802015The CDX1-microRNA-215 axis regulates colorectal cancer stem cell differentiation.43
239815752014MiR-215 modulates gastric cancer cell proliferation by targeting RB1.32
267168952016miR-215 promotes malignant progression of gastric cancer by targeting RUNX1.15
288873062017The long noncoding RNA PCAT-1 links the microRNA miR-215 to oncogene CRKL-mediated signaling in hepatocellular carcinoma.14
266766582016miR-215 functions as a tumor suppressor in epithelial ovarian cancer through regulation of the X-chromosome-linked inhibitor of apoptosis.13

Citation

Dessen P

MIR215 (microRNA 215)

Atlas Genet Cytogenet Oncol Haematol. 2009-01-01

Online version: http://atlasgeneticsoncology.org/gene/50629/mir215-(microrna-215)