CT45A1 (cancer/testis antigen family 45 member A1)

2009-03-01  

Identity

HGNC
CT45A1
LOCATION
Xq26.3
LOCUSID
541466
ALIAS
CT45,CT45-1,CT45.1

Other Information

Locus ID:

NCBI: 541466
MIM: 300648
HGNC: 33267
Ensembl: ENSG00000268940

Variants:

dbSNP: 541466
ClinVar: 541466
TCGA: ENSG00000268940
COSMIC: CT45A1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000268940ENST00000594117Q5HYN5
ENSG00000268940ENST00000594565Q5HYN5

Expression (GTEx)

0
1
2
3
4
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
379244562024Cancer/testis-45A1 promotes cervical cancer cell tumorigenesis and drug resistance by activating oncogenic SRC and downstream signaling pathways.0
379244562024Cancer/testis-45A1 promotes cervical cancer cell tumorigenesis and drug resistance by activating oncogenic SRC and downstream signaling pathways.0
336029622021YBX2 and cancer testis antigen 45 contribute to stemness, chemoresistance and a high degree of malignancy in human endometrial cancer.6
341727172021CT45A1 promotes the metastasis of osteosarcoma cells in vitro and in vivo through β-catenin.9
345034442021Uev1A promotes breast cancer cell migration by up-regulating CT45A expression via the AKT pathway.4
336029622021YBX2 and cancer testis antigen 45 contribute to stemness, chemoresistance and a high degree of malignancy in human endometrial cancer.6
341727172021CT45A1 promotes the metastasis of osteosarcoma cells in vitro and in vivo through β-catenin.9
345034442021Uev1A promotes breast cancer cell migration by up-regulating CT45A expression via the AKT pathway.4
289015092017CT45A1 siRNA silencing suppresses the proliferation, metastasis and invasion of lung cancer cells by downregulating the ERK/CREB signaling pathway.16
289015092017CT45A1 siRNA silencing suppresses the proliferation, metastasis and invasion of lung cancer cells by downregulating the ERK/CREB signaling pathway.16
260987112015DNA hypomethylation-mediated activation of Cancer/Testis Antigen 45 (CT45) genes is associated with disease progression and reduced survival in epithelial ovarian cancer.37
260987112015DNA hypomethylation-mediated activation of Cancer/Testis Antigen 45 (CT45) genes is associated with disease progression and reduced survival in epithelial ovarian cancer.37
249010562014CT45A1 acts as a new proto-oncogene to trigger tumorigenesis and cancer metastasis.41
249010562014CT45A1 acts as a new proto-oncogene to trigger tumorigenesis and cancer metastasis.41
201336972010Expression of cancer testis antigen CT45 in classical Hodgkin lymphoma and other B-cell lymphomas.24

Citation

Dessen P

CT45A1 (cancer/testis antigen family 45 member A1)

Atlas Genet Cytogenet Oncol Haematol. 2009-03-01

Online version: http://atlasgeneticsoncology.org/gene/50804/js/lib/css/template-card.css