PID1 (phosphotyrosine interaction domain containing 1)

2009-05-01 Affiliation

Identity

HGNC

PID1

LOCATION

2q36.3

LOCUSID

55022

ALIAS

HMFN2073,NYGGF4,P-CLI1,PCLI1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 55022
MIM: 612930
HGNC: 26084
Ensembl: ENSG00000153823

Variants:

dbSNP: 55022
ClinVar: 55022
TCGA: ENSG00000153823
COSMIC: PID1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000153823	ENST00000354069	Q7Z2X4
ENSG00000153823	ENST00000392054	Q7Z2X4
ENSG00000153823	ENST00000392055	Q7Z2X4
ENSG00000153823	ENST00000409462	Q7Z2X4
ENSG00000153823	ENST00000534952	F5H314

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
31339628	2019	Overexpression of PID1 reduces high density lipoprotein level and functionality in swine.	4
31339628	2019	Overexpression of PID1 reduces high density lipoprotein level and functionality in swine.	4
30100244	2018	The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins.	9
30100244	2018	The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins.	9
24300787	2014	PID1 (NYGGF4), a new growth-inhibitory gene in embryonal brain tumors and gliomas.	20
24300787	2014	PID1 (NYGGF4), a new growth-inhibitory gene in embryonal brain tumors and gliomas.	20
23274913	2013	Overexpression of TFAM protects 3T3-L1 adipocytes from NYGGF4 (PID1) overexpression-induced insulin resistance and mitochondrial dysfunction.	5
23274913	2013	Overexpression of TFAM protects 3T3-L1 adipocytes from NYGGF4 (PID1) overexpression-induced insulin resistance and mitochondrial dysfunction.	5
22284633	2012	NYGGF4 as a new therapeutic target for obesity-associated insulin resistance.	1
22968630	2012	NYGGF4 (PID1) effects on insulin resistance are reversed by metformin in 3T3-L1 adipocytes.	3
22284633	2012	NYGGF4 as a new therapeutic target for obesity-associated insulin resistance.	1
22968630	2012	NYGGF4 (PID1) effects on insulin resistance are reversed by metformin in 3T3-L1 adipocytes.	3
20010835	2010	Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.	309
20140872	2010	[Expression of the NYGGF4 gene during human preadipocyte differentiation and the regulative role of tumor necrosis factor-alpha].	0
20165904	2010	Overexpression of NYGGF4 (PID1) induces mitochondrial impairment in 3T3-L1 adipocytes.	6

Citation

Dessen P

PID1 (phosphotyrosine interaction domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2009-05-01

Online version: http://atlasgeneticsoncology.org/gene/50893/teaching-explorer/css/template-card.css