NPAT (nuclear protein, coactivator of histone transcription)

2009-05-01  

Identity

HGNC
NPAT
LOCATION
11q22.3
LOCUSID
4863
ALIAS
E14,E14/NPAT,p220

Other Information

Locus ID:

NCBI: 4863
MIM: 601448
HGNC: 7896
Ensembl: ENSG00000149308

Variants:

dbSNP: 4863
ClinVar: 4863
TCGA: ENSG00000149308
COSMIC: NPAT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149308ENST00000278612Q14207
ENSG00000149308ENST00000527296H0YET3
ENSG00000149308ENST00000531384E9PKJ1

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
387780812024Germline NPAT inactivating variants as cause of hereditary colorectal cancer.1
387780812024Germline NPAT inactivating variants as cause of hereditary colorectal cancer.1
341974852021The genetic association of the transcription factor NPAT with glycemic response to metformin involves regulation of fuel selection.0
341974852021The genetic association of the transcription factor NPAT with glycemic response to metformin involves regulation of fuel selection.0
327222822020Structural Analysis of the SANT/Myb Domain of FLASH and YARP Proteins and Their Complex with the C-Terminal Fragment of NPAT by NMR Spectroscopy and Computer Simulations.4
327222822020Structural Analysis of the SANT/Myb Domain of FLASH and YARP Proteins and Their Complex with the C-Terminal Fragment of NPAT by NMR Spectroscopy and Computer Simulations.4
264299162015Interaction of Heat Shock Protein Cpn10 with the Cyclin E/Cdk2 Substrate Nuclear Protein Ataxia-Telangiectasia (NPAT) Is Involved in Regulating Histone Transcription.9
264299162015Interaction of Heat Shock Protein Cpn10 with the Cyclin E/Cdk2 Substrate Nuclear Protein Ataxia-Telangiectasia (NPAT) Is Involved in Regulating Histone Transcription.9
253391772014A conserved interaction that is essential for the biogenesis of histone locus bodies.29
253391772014A conserved interaction that is essential for the biogenesis of histone locus bodies.29
210506722011Genetic variants of NPAT-ATM and AURKA are associated with an early adverse reaction in the gastrointestinal tract of patients with cervical cancer treated with pelvic radiation therapy.11
210506722011Genetic variants of NPAT-ATM and AURKA are associated with an early adverse reaction in the gastrointestinal tract of patients with cervical cancer treated with pelvic radiation therapy.11
215620392011Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma.29
210506722011Genetic variants of NPAT-ATM and AURKA are associated with an early adverse reaction in the gastrointestinal tract of patients with cervical cancer treated with pelvic radiation therapy.11
210506722011Genetic variants of NPAT-ATM and AURKA are associated with an early adverse reaction in the gastrointestinal tract of patients with cervical cancer treated with pelvic radiation therapy.11

Citation

Dessen P

NPAT (nuclear protein, coactivator of histone transcription)

Atlas Genet Cytogenet Oncol Haematol. 2009-05-01

Online version: http://atlasgeneticsoncology.org/gene/50920/haematological-explorer/css/card-gene.css