LSM10 (LSM10, U7 small nuclear RNA associated)

2009-05-01 Affiliation

Identity

HGNC

LSM10

LOCATION

1p34.3

LOCUSID

84967

ALIAS

MST074,MSTP074

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 84967
MIM: 617909
HGNC: 17562
Ensembl: ENSG00000181817

Variants:

dbSNP: 84967
ClinVar: 84967
TCGA: ENSG00000181817
COSMIC: LSM10

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000181817	ENST00000315732	Q969L4

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Gene Expression	REACTOME	R-HSA-74160
RNA Polymerase II Transcription	REACTOME	R-HSA-73857
RNA Polymerase II Transcription Termination	REACTOME	R-HSA-73856
Cleavage of Growing Transcript in the Termination Region	REACTOME	R-HSA-109688
Processing of Capped Intronless Pre-mRNA	REACTOME	R-HSA-75067
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	REACTOME	R-HSA-77588
SLBP independent Processing of Histone Pre-mRNAs	REACTOME	R-HSA-111367

References

Pubmed ID	Year	Title	Citations
31819999	2020	Composition and processing activity of a semi-recombinant holo U7 snRNP.	10
31819999	2020	Composition and processing activity of a semi-recombinant holo U7 snRNP.	10
28289156	2017	U7 snRNP is recruited to histone pre-mRNA in a FLASH-dependent manner by two separate regions of the stem-loop binding protein.	21
28289156	2017	U7 snRNP is recruited to histone pre-mRNA in a FLASH-dependent manner by two separate regions of the stem-loop binding protein.	21
19277982	2009	The subnuclear organization of histone gene regulatory proteins and 3' end processing factors of normal somatic and embryonic stem cells is compromised in selected human cancer cell types.	27
19277982	2009	The subnuclear organization of histone gene regulatory proteins and 3' end processing factors of normal somatic and embryonic stem cells is compromised in selected human cancer cell types.	27
16914750	2006	ZFP100, a component of the active U7 snRNP limiting for histone pre-mRNA processing, is required for entry into S phase.	21
16914750	2006	ZFP100, a component of the active U7 snRNP limiting for histone pre-mRNA processing, is required for entry into S phase.	21
16087681	2005	Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.	17
16087681	2005	Toward an assembly line for U7 snRNPs: interactions of U7-specific Lsm proteins with PRMT5 and SMN complexes.	17
11574479	2001	Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.	90
11574479	2001	Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.	90

Citation

Dessen P

LSM10 (LSM10, U7 small nuclear RNA associated)

Atlas Genet Cytogenet Oncol Haematol. 2009-05-01

Online version: http://atlasgeneticsoncology.org/gene/50921/cancer-prone-explorer/favicon/css/card-gene.css