SEMA6D (semaphorin 6D)

2009-06-01 Affiliation

Identity

HGNC

SEMA6D

LOCATION

15q21.1

LOCUSID

80031

ALIAS

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 80031
MIM: 609295
HGNC: 16770
Ensembl: ENSG00000137872

Variants:

dbSNP: 80031
ClinVar: 80031
TCGA: ENSG00000137872
COSMIC: SEMA6D

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000137872	ENST00000316364	Q8NFY4
ENSG00000137872	ENST00000354744	Q8NFY4
ENSG00000137872	ENST00000355997	Q8NFY4
ENSG00000137872	ENST00000358066	Q8NFY4
ENSG00000137872	ENST00000389425	Q8NFY4
ENSG00000137872	ENST00000389428	Q8NFY4
ENSG00000137872	ENST00000536845	Q8NFY4
ENSG00000137872	ENST00000558014	Q8NFY4
ENSG00000137872	ENST00000558816	Q8NFY4
ENSG00000137872	ENST00000559064	H0YM97
ENSG00000137872	ENST00000559184	H0YL82
ENSG00000137872	ENST00000559196	H0YMV0
ENSG00000137872	ENST00000560006	H0YMP7
ENSG00000137872	ENST00000561133	H0YMA6

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Axon guidance	KEGG	ko04360
Axon guidance	KEGG	hsa04360
Developmental Biology	REACTOME	R-HSA-1266738
Axon guidance	REACTOME	R-HSA-422475
Semaphorin interactions	REACTOME	R-HSA-373755
Other semaphorin interactions	REACTOME	R-HSA-416700

References

Pubmed ID	Year	Title	Citations
33960276	2021	Neuroimaging genetic associations between SEMA6D, brain structure, and reading skills.	3
33960276	2021	Neuroimaging genetic associations between SEMA6D, brain structure, and reading skills.	3
32472335	2020	CircUBAP2 promotes SEMA6D expression to enhance the cisplatin resistance in osteosarcoma through sponging miR-506-3p by activating Wnt/β-catenin signaling pathway.	19
32472335	2020	CircUBAP2 promotes SEMA6D expression to enhance the cisplatin resistance in osteosarcoma through sponging miR-506-3p by activating Wnt/β-catenin signaling pathway.	19
31814570	2019	[Semaphorin 6D and Snail are highly expressed in gastric cancer and positively correlated with malignant clinicopathological indexes].	4
31814570	2019	[Semaphorin 6D and Snail are highly expressed in gastric cancer and positively correlated with malignant clinicopathological indexes].	4
30592759	2018	The association of semaphorins 3C, 5A and 6D with liver fibrosis stage in chronic hepatitis C.	6
30592759	2018	The association of semaphorins 3C, 5A and 6D with liver fibrosis stage in chronic hepatitis C.	6
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	15
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	15
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	105
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	105
17143962	2006	Expression of semaphorin 6D in gastric carcinoma and its significance.	16
17143962	2006	Expression of semaphorin 6D in gastric carcinoma and its significance.	16
12110693	2002	Identification, characterization, and functional study of the two novel human members of the semaphorin gene family.	25

Citation

Dessen P

SEMA6D (semaphorin 6D)

Atlas Genet Cytogenet Oncol Haematol. 2009-06-01

Online version: http://atlasgeneticsoncology.org/gene/50970/img/js/lib/css/template-nav.css