GFAP (glial fibrillary acidic protein)

2009-06-01  

Identity

HGNC
GFAP
LOCATION
17q21.31
LOCUSID
2670
ALIAS
ALXDRD
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2670
MIM: 137780
HGNC: 4235
Ensembl: ENSG00000131095

Variants:

dbSNP: 2670
ClinVar: 2670
TCGA: ENSG00000131095
COSMIC: GFAP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000131095ENST00000253408A0A1X7SBR3
ENSG00000131095ENST00000376990B4DIR1
ENSG00000131095ENST00000435360P14136
ENSG00000131095ENST00000585728K7EJK1
ENSG00000131095ENST00000586125K7EPI4
ENSG00000131095ENST00000586793A0A1X7SCE1
ENSG00000131095ENST00000588037K7ELP4
ENSG00000131095ENST00000588316K7EKH9
ENSG00000131095ENST00000588735P14136
ENSG00000131095ENST00000588957K7EKD1
ENSG00000131095ENST00000591880K7EPT8
ENSG00000131095ENST00000592320K7EJU1
ENSG00000131095ENST00000593179A0A0G2JLI8
ENSG00000131095ENST00000638281P14136
ENSG00000131095ENST00000638304A0A1W2PPA3
ENSG00000131095ENST00000638400A0A1W2PPL2
ENSG00000131095ENST00000638618A0A1W2PRT3
ENSG00000131095ENST00000639042A0A1W2PS58
ENSG00000131095ENST00000639243A0A1W2PPF0
ENSG00000131095ENST00000639277A0A1W2PR46
ENSG00000131095ENST00000639369A0A1W2PP21
ENSG00000131095ENST00000639921A0A1W2PQU7
ENSG00000131095ENST00000640545A0A1W2PQ25
ENSG00000131095ENST00000640859A0A1W2PQS4

Expression (GTEx)

0
1000
2000
3000
4000
5000
6000
7000
8000
9000
10000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Jak-STAT signaling pathwayKEGGko04630
Jak-STAT signaling pathwayKEGGhsa04630
Signal TransductionREACTOMER-HSA-162582
Signaling by ERBB4REACTOMER-HSA-1236394
Nuclear signaling by ERBB4REACTOMER-HSA-1251985

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
375308942024Associations of plasma NfL, GFAP, and t-tau with cerebral small vessel disease and incident dementia: longitudinal data of the AGES-Reykjavik Study.2
376900712024Astrocyte biomarkers GFAP and YKL-40 mediate early Alzheimer's disease progression.9
377233712024The role of plasma neurofilament light chain and glial fibrillary acidic protein in subjective cognitive decline and mild cognitive impairment.3
381119722024Serum glial fibrillary acidic protein and disability progression in progressive multiple sclerosis.3
381453192024Plasma glial fibrillary acidic protein levels correlate with paramagnetic rim lesions in people with radiologically isolated syndrome.0
381731492024Glial Fibrillary Acidic Protein: Diagnostic and Prognostic Role in Psychomotor Development Dynamics in Patients with Congenital Heart Defects after Cardiovascular Surgery.0
383398192024Relationship between increased serum neurofilament light chain and glial fibrillary acidic protein levels with non-motor symptoms in patients with Parkinson's disease.0
387822072024Glial fibrillary acidic protein is pathologically modified in Alexander disease.0
375308942024Associations of plasma NfL, GFAP, and t-tau with cerebral small vessel disease and incident dementia: longitudinal data of the AGES-Reykjavik Study.2
376900712024Astrocyte biomarkers GFAP and YKL-40 mediate early Alzheimer's disease progression.9
377233712024The role of plasma neurofilament light chain and glial fibrillary acidic protein in subjective cognitive decline and mild cognitive impairment.3
381119722024Serum glial fibrillary acidic protein and disability progression in progressive multiple sclerosis.3
381453192024Plasma glial fibrillary acidic protein levels correlate with paramagnetic rim lesions in people with radiologically isolated syndrome.0
381731492024Glial Fibrillary Acidic Protein: Diagnostic and Prognostic Role in Psychomotor Development Dynamics in Patients with Congenital Heart Defects after Cardiovascular Surgery.0
383398192024Relationship between increased serum neurofilament light chain and glial fibrillary acidic protein levels with non-motor symptoms in patients with Parkinson's disease.0

Citation

Dessen P

GFAP (glial fibrillary acidic protein)

Atlas Genet Cytogenet Oncol Haematol. 2009-06-01

Online version: http://atlasgeneticsoncology.org/gene/50981/deep-insight-explorer/gene-fusions/js/_common.js