MIR127 (microRNA 127)

2009-08-01  

Identity

HGNC
LOCATION
14q32.2
LOCUSID
ALIAS
MIRN127,miRNA127,mir-127

Other Information

Locus ID:

NCBI: 406914
MIM: 611709
HGNC: 31509
Ensembl: ENSG00000207608
miRBase:

Variants:

dbSNP: 406914
ClinVar: 406914
TCGA: ENSG00000207608
COSMIC: MIR127

RNA/Proteins

References

Pubmed IDYearTitleCitations
195302372010B-cell differentiation in EBV-positive Burkitt lymphoma is impaired at posttranscriptional level by miRNA-altered expression.38
237623302013A feedback inhibition between miRNA-127 and TGFβ/c-Jun cascade in HCC cell migration via MMP13.33
267081472016MicroRNA-127-5p targets the biliverdin reductase B/nuclear factor-κB pathway to suppress cell growth in hepatocellular carcinoma cells.15
275717442016MicroRNA-127-3p acts as a tumor suppressor in epithelial ovarian cancer by regulating the BAG5 gene.15
224336062012miR-127-5p targets the 3'UTR of human β-F1-ATPase mRNA and inhibits its translation.14
271269552016MicroRNA-127-5p regulates osteopontin expression and osteopontin-mediated proliferation of human chondrocytes.14
286361012018Knockdown of lncRNA MEG3 inhibits viability, migration, and invasion and promotes apoptosis by sponging miR-127 in osteosarcoma cell.13
288660932017MiR-127 and miR-376a act as tumor suppressors by in vivo targeting of COA1 and PDIA6 in giant cell tumor of bone.12
266559972016Restoration of miR-127-3p and miR-376a-3p counteracts the neoplastic phenotype of giant cell tumor of bone derived stromal cells by targeting COA1, GLE1 and PDIA6.11
276458942016MicroRNA-127 is a tumor suppressor in human esophageal squamous cell carcinoma through the regulation of oncogene FMNL3.11

Citation

Dessen P

MIR127 (microRNA 127)

Atlas Genet Cytogenet Oncol Haematol. 2009-08-01

Online version: http://atlasgeneticsoncology.org/gene/51005/mir127-(microrna-127)