CST1 (cystatin SN)

2009-09-01  

Identity

HGNC
CST1
LOCATION
20p11.21
LOCUSID
1469
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1469
MIM: 123855
HGNC: 2473
Ensembl: ENSG00000170373

Variants:

dbSNP: 1469
ClinVar: 1469
TCGA: ENSG00000170373
COSMIC: CST1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170373ENST00000304749P01037
ENSG00000170373ENST00000398402P01037

Expression (GTEx)

0
1
2
3
4
5
6
7
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Salivary secretionKEGGko04970
Salivary secretionKEGGhsa04970

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382703262024The functional role of CST1 and CCL26 in asthma development.0
382703262024The functional role of CST1 and CCL26 in asthma development.0
368483492023MiR-942-5p inhibits tumor migration and invasion through targeting CST1 in esophageal squamous cell carcinoma.8
369589852023Cystatin SN in type 2 inflammatory airway diseases.1
370265022023Epithelium-derived cystatin SN inhibits house dust mite protease activity in allergic asthma.2
378947952023Meibomian Gland Dysfunction Is Associated with Low Levels of Immunoglobulin Chains and Cystatin-SN.2
380774392023Combination of serum CST1 and HE4 for early diagnosis of endometrial cancer.0
368483492023MiR-942-5p inhibits tumor migration and invasion through targeting CST1 in esophageal squamous cell carcinoma.8
369589852023Cystatin SN in type 2 inflammatory airway diseases.1
370265022023Epithelium-derived cystatin SN inhibits house dust mite protease activity in allergic asthma.2
378947952023Meibomian Gland Dysfunction Is Associated with Low Levels of Immunoglobulin Chains and Cystatin-SN.2
380774392023Combination of serum CST1 and HE4 for early diagnosis of endometrial cancer.0
356374322022Cystatin SN promotes epithelial-mesenchymal transition and serves as a prognostic biomarker in lung adenocarcinoma.4
359534392022MicroRNA-375 inhibits laryngeal squamous cell carcinoma progression via targeting CST1.3
356374322022Cystatin SN promotes epithelial-mesenchymal transition and serves as a prognostic biomarker in lung adenocarcinoma.4

Citation

Dessen P

CST1 (cystatin SN)

Atlas Genet Cytogenet Oncol Haematol. 2009-09-01

Online version: http://atlasgeneticsoncology.org/gene/51081/meetings/js/lib/all.min.js