SLC2A12 (solute carrier family 2 member 12)

2009-10-01  

Identity

HGNC
LOCATION
6q23.2
LOCUSID
ALIAS
GLUT12,GLUT8
FUSION GENES

Other Information

Locus ID:

NCBI: 154091
MIM: 610372
HGNC: 18067
Ensembl: ENSG00000146411

Variants:

dbSNP: 154091
ClinVar: 154091
TCGA: ENSG00000146411
COSMIC: SLC2A12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000146411ENST00000275230Q8TD20

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366
Facilitative Na+-independent glucose transportersREACTOMER-HSA-428790

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
365940842023Inhibition of androgen receptor enhanced the anticancer effects of everolimus through targeting glucose transporter 12.1
379400662023Hypoxia promotes the growth and metastasis of ovarian cancer cells by suppressing ferroptosis via upregulating SLC2A12.2
365940842023Inhibition of androgen receptor enhanced the anticancer effects of everolimus through targeting glucose transporter 12.1
379400662023Hypoxia promotes the growth and metastasis of ovarian cancer cells by suppressing ferroptosis via upregulating SLC2A12.2
347916272021Epithelial mesenchymal transition regulator TWIST1 transcription factor stimulates glucose uptake through upregulation of GLUT1, GLUT3, and GLUT12 in vitro.1
347916272021Epithelial mesenchymal transition regulator TWIST1 transcription factor stimulates glucose uptake through upregulation of GLUT1, GLUT3, and GLUT12 in vitro.1
329469642020Let-7a-5p inhibits triple-negative breast tumor growth and metastasis through GLUT12-mediated warburg effect.29
330774972020Alternative Splicing and Cleavage of GLUT8.12
329469642020Let-7a-5p inhibits triple-negative breast tumor growth and metastasis through GLUT12-mediated warburg effect.29
330774972020Alternative Splicing and Cleavage of GLUT8.12
303521232019GLUT12 expression and regulation in murine small intestine and human Caco-2 cells.4
310022002019GLUT12 and adipose tissue: Expression, regulation and its relation with obesity in mice.6
303521232019GLUT12 expression and regulation in murine small intestine and human Caco-2 cells.4
310022002019GLUT12 and adipose tissue: Expression, regulation and its relation with obesity in mice.6
291874482017Potential Roles of GLUT12 for Glucose Sensing and Cellular Migration in MCF-7 Human Breast Cancer Cells Under High Glucose Conditions.8

Citation

Dessen P

SLC2A12 (solute carrier family 2 member 12)

Atlas Genet Cytogenet Oncol Haematol. 2009-10-01

Online version: http://atlasgeneticsoncology.org/gene/51172/css/css/lib/dataTables.bootstrap.min.css