SLC31A2 (solute carrier family 31 member 2)

2009-11-01  

Identity

HGNC
SLC31A2
LOCATION
9q32
LOCUSID
1318
ALIAS
COPT2,CTR2,hCTR2

Other Information

Locus ID:

NCBI: 1318
MIM: 603088
HGNC: 11017
Ensembl: ENSG00000136867

Variants:

dbSNP: 1318
ClinVar: 1318
TCGA: ENSG00000136867
COSMIC: SLC31A2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136867ENST00000259392O15432
ENSG00000136867ENST00000259392Q53X94
ENSG00000136867ENST00000374220F2Z3D2

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
285070972017Gene duplication and neo-functionalization in the evolutionary and functional divergence of the metazoan copper transporters Ctr1 and Ctr2.16
287371292017Association between polymorphisms in CTR1, CTR2, ATP7A, and ATP7B and platinum resistance in epithelial ovarian cancer.0
285070972017Gene duplication and neo-functionalization in the evolutionary and functional divergence of the metazoan copper transporters Ctr1 and Ctr2.16
287371292017Association between polymorphisms in CTR1, CTR2, ATP7A, and ATP7B and platinum resistance in epithelial ovarian cancer.0
264115502016Decreased expression of CTR2 predicts poor prognosis of patients with clear cell renal cell carcinoma.6
264115502016Decreased expression of CTR2 predicts poor prognosis of patients with clear cell renal cell carcinoma.6
247037122015The role of Ctr1 and Ctr2 in mammalian copper homeostasis and platinum-based chemotherapy.25
262053682015The copper transporter 1 (CTR1) is required to maintain the stability of copper transporter 2 (CTR2).9
247037122015The role of Ctr1 and Ctr2 in mammalian copper homeostasis and platinum-based chemotherapy.25
262053682015The copper transporter 1 (CTR1) is required to maintain the stability of copper transporter 2 (CTR2).9
245222732014Copper transporter 2 regulates intracellular copper and sensitivity to cisplatin.25
245222732014Copper transporter 2 regulates intracellular copper and sensitivity to cisplatin.25
235647802013Association of copper transporter expression with platinum resistance in epithelial ovarian cancer.17
235647802013Association of copper transporter expression with platinum resistance in epithelial ovarian cancer.17
195091352009Copper transporter 2 regulates the cellular accumulation and cytotoxicity of Cisplatin and Carboplatin.67

Citation

Dessen P

SLC31A2 (solute carrier family 31 member 2)

Atlas Genet Cytogenet Oncol Haematol. 2009-11-01

Online version: http://atlasgeneticsoncology.org/gene/51206/teaching-explorer/js/template.js