IFNK (interferon kappa)

2010-01-01  

Identity

HGNC
LOCATION
9p21.2
LOCUSID
ALIAS
IFNT1,INFE1
FUSION GENES

Other Information

Locus ID:

NCBI: 56832
MIM: 615326
HGNC: 21714
Ensembl: ENSG00000147896

Variants:

dbSNP: 56832
ClinVar: 56832
TCGA: ENSG00000147896
COSMIC: IFNK

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147896ENST00000276943Q9P0W0

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Cytokine-cytokine receptor interactionKEGGko04060
Jak-STAT signaling pathwayKEGGko04630
Cytokine-cytokine receptor interactionKEGGhsa04060
Jak-STAT signaling pathwayKEGGhsa04630
RIG-I-like receptor signaling pathwayKEGGko04622
RIG-I-like receptor signaling pathwayKEGGhsa04622

References

Pubmed IDYearTitleCitations
186151562008Genome-wide association scan identifies candidate polymorphisms associated with differential response to anti-TNF treatment in rheumatoid arthritis.68
218494312011High-risk human papillomaviruses repress constitutive kappa interferon transcription via E6 to prevent pathogen recognition receptor and antiviral-gene expression.60
198876122009Epigenetic silencing of interferon-kappa in human papillomavirus type 16-positive cells.45
123911922002Regulatory effect of IFN-kappa, a novel type I IFN, on cytokine production by cells of the innate immune system.30
246142102014E2 proteins of high risk human papillomaviruses down-modulate STING and IFN-κ transcription in keratinocytes.29
207066082010The role of genetic variation near interferon-kappa in systemic lupus erythematosus.22
207066082010The role of genetic variation near interferon-kappa in systemic lupus erythematosus.22
205748432010Associations of 9p21 variants with cutaneous malignant melanoma, nevi, and pigmentation phenotypes in melanoma-prone families with and without CDKN2A mutations.18
206348912010Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.18
264911692016Interferon Kappa Inhibits Human Papillomavirus 31 Transcription by Inducing Sp100 Proteins.16

Citation

Dessen P

IFNK (interferon kappa)

Atlas Genet Cytogenet Oncol Haematol. 2010-01-01

Online version: http://atlasgeneticsoncology.org/gene/51313/ifnk