CHMP5 (charged multivesicular body protein 5)

2010-02-01  

Identity

HGNC
LOCATION
9p13.3
LOCUSID
ALIAS
C9orf83,CGI-34,HSPC177,PNAS-2,SNF7DC2,Vps60
FUSION GENES

Other Information

Locus ID:

NCBI: 51510
MIM: 610900
HGNC: 26942
Ensembl: ENSG00000086065

Variants:

dbSNP: 51510
ClinVar: 51510
TCGA: ENSG00000086065
COSMIC: CHMP5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000086065ENST00000223500Q9NZZ3
ENSG00000086065ENST00000419016Q9NZZ3

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
ESCRT-III complexKEGGhsa_M00412
ESCRT-III complexKEGGM00412
DiseaseREACTOMER-HSA-1643685
Infectious diseaseREACTOMER-HSA-5663205
HIV InfectionREACTOMER-HSA-162906
HIV Life CycleREACTOMER-HSA-162587
Late Phase of HIV Life CycleREACTOMER-HSA-162599
Budding and maturation of HIV virionREACTOMER-HSA-162588
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Endosomal Sorting Complex Required For Transport (ESCRT)REACTOMER-HSA-917729

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
256376302015A novel mechanism of regulating the ATPase VPS4 by its cofactor LIP5 and the endosomal sorting complex required for transport (ESCRT)-III protein CHMP5.14
236195692013The role of charged multivesicular body protein 5 in programmed cell death in leukemic cells.2
303340652018MicroRNA 429 regulates the expression of CHMP5 in the inflammatory colitis and colorectal cancer cells.2
178557962006PNAS-2: a novel gene probably participating in leukemogenesis.1
268215762016Charged MVB protein 5 is involved in T-cell receptor signaling.1
177087942007[Correlation between expression of apoptosis-related gene pnas-2 and leukemia].0
184266492008[Expression spectra of apoptosis-related gene pnas-2].0

Citation

Dessen P

CHMP5 (charged multivesicular body protein 5)

Atlas Genet Cytogenet Oncol Haematol. 2010-02-01

Online version: http://atlasgeneticsoncology.org/gene/51321/chmp5