CYB5B (cytochrome b5 type B)

2010-06-01  

Identity

HGNC
LOCATION
16q22.1
LOCUSID
ALIAS
CYB5-M,CYPB5M,OMB5
FUSION GENES

Other Information

Locus ID:

NCBI: 80777
MIM: 611964
HGNC: 24374
Ensembl: ENSG00000103018

Variants:

dbSNP: 80777
ClinVar: 80777
TCGA: ENSG00000103018
COSMIC: CYB5B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000103018ENST00000307892O43169
ENSG00000103018ENST00000515314D6RFH4
ENSG00000103018ENST00000561792H3BUX2
ENSG00000103018ENST00000568237J3QR91

Expression (GTEx)

0
50
100
150
200
250
300
350

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase 1 - Functionalization of compoundsREACTOMER-HSA-211945

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
201003552010Constitutively overexpressed 21 kDa protein in Hodgkin lymphoma and aggressive non-Hodgkin lymphomas identified as cytochrome B5b (CYB5B).6
147392752004Neuronal calcium sensor protein visinin-like protein-3 interacts with microsomal cytochrome b5 in a Ca2+-dependent manner.5
237036162013The involvement of mitochondrial amidoxime reducing components 1 and 2 and mitochondrial cytochrome b5 in N-reductive metabolism in human cells.5
118672652002Assessment of the ability of type 2 cytochrome b5 to modulate 17,20-lyase activity of human P450c17.4
215745702011Accommodating a nonconservative internal mutation by water-mediated hydrogen bonding between β-sheet strands: a comparison of human and rat type B (mitochondrial) cytochrome b5.3

Citation

Dessen P

CYB5B (cytochrome b5 type B)

Atlas Genet Cytogenet Oncol Haematol. 2010-06-01

Online version: http://atlasgeneticsoncology.org/gene/51507/cyb5b-(cytochrome-b5-type-b)