CORO1C (coronin 1C)

2010-10-01  

Identity

HGNC
CORO1C
LOCATION
12q24.11
LOCUSID
23603
ALIAS
HCRNN4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23603
MIM: 605269
HGNC: 2254
Ensembl: ENSG00000110880

Variants:

dbSNP: 23603
ClinVar: 23603
TCGA: ENSG00000110880
COSMIC: CORO1C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000110880ENST00000261401Q9ULV4
ENSG00000110880ENST00000261401A0A024RBI5
ENSG00000110880ENST00000420959Q9ULV4
ENSG00000110880ENST00000421578B4E3S0
ENSG00000110880ENST00000541050Q9ULV4
ENSG00000110880ENST00000541050A0A024RBI5
ENSG00000110880ENST00000546571F8VSA4
ENSG00000110880ENST00000546705H0YHL7
ENSG00000110880ENST00000547294F8VVB7
ENSG00000110880ENST00000549772Q9ULV4
ENSG00000110880ENST00000550032F8VTT6
ENSG00000110880ENST00000550542F8VUX3
ENSG00000110880ENST00000551044F8W1H8
ENSG00000110880ENST00000551550F8VRE9
ENSG00000110880ENST00000552871F8VV53

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
290748492017The circular RNA circBIRC6 participates in the molecular circuitry controlling human pluripotency.54
274995212016The Power of Human Protective Modifiers: PLS3 and CORO1C Unravel Impaired Endocytosis in Spinal Muscular Atrophy and Rescue SMA Phenotype.45
255187412015Downregulation of the microRNA-1/133a cluster enhances cancer cell migration and invasion in lung-squamous cell carcinoma via regulation of Coronin1C.28
123777792002Oligomerization, F-actin interaction, and membrane association of the ubiquitous mammalian coronin 3 are mediated by its carboxyl terminus.27
172749802007Coronin 3 involvement in F-actin-dependent processes at the cell cortex.19
194235402009Common variation in genes related to innate immunity and risk of adult glioma.19
229742332012Coronin 3 promotes gastric cancer metastasis via the up-regulation of MMP-9 and cathepsin K.19
206901622010Primary effusion lymphoma: genomic profiling revealed amplification of SELPLG and CORO1C encoding for proteins important for cell migration.18
283021182017YBX1 gene silencing inhibits migratory and invasive potential via CORO1C in breast cancer in vitro.14
204069642010Risk of meningioma and common variation in genes related to innate immunity.12

Citation

Dessen P

CORO1C (coronin 1C)

Atlas Genet Cytogenet Oncol Haematol. 2010-10-01

Online version: http://atlasgeneticsoncology.org/gene/51722/coro1c