HOXD1 (homeobox D1)

2010-11-01  

Identity

HGNC
HOXD1
LOCATION
2q31.1
LOCUSID
3231
ALIAS
HOX4,HOX4G,Hox-4.7
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3231
MIM: 142987
HGNC: 5132
Ensembl: ENSG00000128645

Variants:

dbSNP: 3231
ClinVar: 3231
TCGA: ENSG00000128645
COSMIC: HOXD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128645ENST00000331462Q9GZZ0

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Activation of HOX genes during differentiationREACTOMER-HSA-5619507
Activation of anterior HOX genes in hindbrain development during early embryogenesisREACTOMER-HSA-5617472

References

Pubmed IDYearTitleCitations
376555552023Homeobox-D 1 and FTO form a transcriptional-epigenetic feedback loop to promote head and neck cancer proliferation.0
378276982023A pan-cancer analysis of the role of HOXD1, HOXD3, and HOXD4 and validation in renal cell carcinoma.0
376555552023Homeobox-D 1 and FTO form a transcriptional-epigenetic feedback loop to promote head and neck cancer proliferation.0
378276982023A pan-cancer analysis of the role of HOXD1, HOXD3, and HOXD4 and validation in renal cell carcinoma.0
335599012021HOXD1 functions as a novel tumor suppressor in kidney renal clear cell carcinoma.10
335599012021HOXD1 functions as a novel tumor suppressor in kidney renal clear cell carcinoma.10
229307472012Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis.43
229307472012Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis.43
215015862011Homeobox D1 regulates angiogenic functions of endothelial cells via integrin β1 expression.10
215015862011Homeobox D1 regulates angiogenic functions of endothelial cells via integrin β1 expression.10
208526322010A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.209
208526322010A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.209
208526322010A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.209
208526322010A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.209
194532612009High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.23

Citation

Dessen P

HOXD1 (homeobox D1)

Atlas Genet Cytogenet Oncol Haematol. 2010-11-01

Online version: http://atlasgeneticsoncology.org/gene/51756/css/lib/js/_common.js