ADGRF1 (adhesion G protein-coupled receptor F1)

2011-02-01  

Identity

HGNC
ADGRF1
LOCATION
6p12.3
LOCUSID
266977
ALIAS
GPR110,KPG_012,PGR19,hGPCR36
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 266977
MIM: 617430
HGNC: 18990
Ensembl: ENSG00000153292

Variants:

dbSNP: 266977
ClinVar: 266977
TCGA: ENSG00000153292
COSMIC: ADGRF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000153292ENST00000283297A0A0C4DH10
ENSG00000153292ENST00000371243Q5T601
ENSG00000153292ENST00000371253Q5T601
ENSG00000153292ENST00000475745H7C4N3
ENSG00000153292ENST00000487323H7C570

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
259183802015Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist.52
288660952017Differential expression of MUC4, GPR110 and IL2RA defines two groups of CRLF2-rearranged acute lymphoblastic leukemia patients with distinct secondary lesions.8
289688392017Polymorphisms in genes related to epithelial-mesenchymal transition and risk of non-small cell lung cancer.6
287288432017Expression and prognostic role of orphan receptor GPR110 in glioma.4
201492562010Orphan receptor GPR110, an oncogene overexpressed in lung and prostate cancer.0
277590032016Orphan GPR110 (ADGRF1) targeted by N-docosahexaenoylethanolamine in development of neurons and cognitive function.0
295721092018N-Docosahexaenoylethanolamine: A neurotrophic and neuroprotective metabolite of docosahexaenoic acid.0
295746362018GPCRs profiling and identification of GPR110 as a potential new target in HER2+ breast cancer.0
306389502019Clinicopathological and prognostic significance of aberrant G protein-couple receptor 110 (GPR110) expression in gastric cancer.0

Citation

Dessen P

ADGRF1 (adhesion G protein-coupled receptor F1)

Atlas Genet Cytogenet Oncol Haematol. 2011-02-01

Online version: http://atlasgeneticsoncology.org/gene/52049/adgrf1-(adhesion-g-protein-coupled-receptor-f1)