MIR425 (microRNA 425)

2011-03-01  

Identity

HGNC
LOCATION
3p21.31
LOCUSID
ALIAS
MIRN425,hsa-mir-425,mir-425

Other Information

Locus ID:

NCBI: 494337
HGNC: 31882
Ensembl: ENSG00000199032
miRBase:

Variants:

dbSNP: 494337
ClinVar: 494337
TCGA: ENSG00000199032
COSMIC: MIR425

RNA/Proteins

Expression (GTEx)

0
1

References

Pubmed IDYearTitleCitations
211189672010Genetic variants in MicroRNA biosynthesis pathways and binding sites modify ovarian cancer risk, survival, and treatment response.59
238676232013Atrial natriuretic peptide is negatively regulated by microRNA-425.40
245716672014NF-kappaB-dependent microRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1β induction.34
268825632016CTNNA3 is a tumor suppressor in hepatocellular carcinomas and is inhibited by miR-425.16
264636312015miR-425 inhibits melanoma metastasis through repression of PI3K-Akt pathway by targeting IGF-1.13
266743782015Enhanced Expression of miR-425 Promotes Esophageal Squamous Cell Carcinoma Tumorigenesis by Targeting SMAD2.10
271320352016Arsenic-induced anti-angiogenesis via miR-425-5p-regulated CCM3.5
281921892017miR-425 regulates inflammatory cytokine production in CD4+ T cells via N-Ras upregulation in primary biliary cholangitis.5
293313762018MicroRNA-425 facilitates pathogenic Th17 cell differentiation by targeting forkhead box O1 (Foxo1) and is associated with inflammatory bowel disease.5
303387982018MiR-425 involves in the development and progression of renal cell carcinoma by inhibiting E2F6.3

Citation

Dessen P

MIR425 (microRNA 425)

Atlas Genet Cytogenet Oncol Haematol. 2011-03-01

Online version: http://atlasgeneticsoncology.org/gene/52128/mir425