PTGFRN (prostaglandin F2 receptor inhibitor)

2011-04-01  

Identity

HGNC
PTGFRN
LOCATION
1p13.1
LOCUSID
5738
ALIAS
CD315,CD9P-1,EWI-F,FPRP,SMAP-6
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5738
MIM: 601204
HGNC: 9601
Ensembl: ENSG00000134247

Variants:

dbSNP: 5738
ClinVar: 5738
TCGA: ENSG00000134247
COSMIC: PTGFRN

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134247ENST00000393203Q9P2B2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
335030702021Identification of Prostaglandin F2 Receptor Negative Regulator (PTGFRN) as an internalizable target in cancer cells for antibody-drug conjugate development.3
335030702021Identification of Prostaglandin F2 Receptor Negative Regulator (PTGFRN) as an internalizable target in cancer cells for antibody-drug conjugate development.3
313772052019The Ig superfamily protein PTGFRN coordinates survival signaling in glioblastoma multiforme.14
313772052019The Ig superfamily protein PTGFRN coordinates survival signaling in glioblastoma multiforme.14
212064922011CD9P-1 expression correlates with the metastatic status of lung cancer, and a truncated form of CD9P-1, GS-168AT2, inhibits in vivo tumour growth.12
212064922011CD9P-1 expression correlates with the metastatic status of lung cancer, and a truncated form of CD9P-1, GS-168AT2, inhibits in vivo tumour growth.12
198502832010Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches.34
198502832010Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches.34
197036042009In situ chemical cross-linking on living cells reveals CD9P-1 cis-oligomer at cell surface.9
197036042009In situ chemical cross-linking on living cells reveals CD9P-1 cis-oligomer at cell surface.9
174071542007The transferrin receptor and the tetraspanin web molecules CD9, CD81, and CD9P-1 are differentially sorted into exosomes after TPA treatment of K562 cells.25
179607392007Glycosylation status of the membrane protein CD9P-1.8
174071542007The transferrin receptor and the tetraspanin web molecules CD9, CD81, and CD9P-1 are differentially sorted into exosomes after TPA treatment of K562 cells.25
179607392007Glycosylation status of the membrane protein CD9P-1.8
165375452006Contrasting effects of EWI proteins, integrins, and protein palmitoylation on cell surface CD9 organization.31

Citation

Dessen P

PTGFRN (prostaglandin F2 receptor inhibitor)

Atlas Genet Cytogenet Oncol Haematol. 2011-04-01

Online version: http://atlasgeneticsoncology.org/gene/52161/gene-fusions-explorer/gene-fusions/css/lib/dataTables.bootstrap.min.css