AKIP1 (A-kinase interacting protein 1)

2011-04-01  

Identity

HGNC
LOCATION
11p15.4
LOCUSID
ALIAS
BCA3,C11orf17
FUSION GENES

Other Information

Locus ID:

NCBI: 56672
MIM: 609191
HGNC: 1170
Ensembl: ENSG00000166452

Variants:

dbSNP: 56672
ClinVar: 56672
TCGA: ENSG00000166452
COSMIC: AKIP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166452ENST00000299576Q9NQ31
ENSG00000166452ENST00000309357Q9NQ31
ENSG00000166452ENST00000309377Q9NQ31
ENSG00000166452ENST00000396648Q9NQ31
ENSG00000166452ENST00000524577E9PNI1
ENSG00000166452ENST00000525005B4DGE2
ENSG00000166452ENST00000529876E9PN38
ENSG00000166452ENST00000529942H0YCH8
ENSG00000166452ENST00000530281E9PPN7
ENSG00000166452ENST00000534147Q9NQ31
ENSG00000166452ENST00000534506E9PN38

Expression (GTEx)

0
5
10
15
20
25
30

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
156300842005A-kinase-interacting protein localizes protein kinase A in the nucleus.52
205621102010A-kinase-interacting protein 1 (AKIP1) acts as a molecular determinant of PKA in NF-kappaB signaling.34
181789622008AKIP1 enhances NF-kappaB-dependent gene expression by promoting the nuclear retention and phosphorylation of p65.25
244130792015Overexpression of AKIP1 promotes angiogenesis and lymphangiogenesis in human esophageal squamous cell carcinoma.20
125274322003Characterization of a novel human breast cancer associated gene (BCA3) encoding an alternatively spliced proline-rich protein.17
233196522013A kinase interacting protein (AKIP1) is a key regulator of cardiac stress.16
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
295206952018AKIP1 promotes angiogenesis and tumor growth by upregulating CXC-chemokines in cervical cancer cells.7
309364612019AKIP1 promotes early recurrence of hepatocellular carcinoma through activating the Wnt/β-catenin/CBP signaling pathway.6

Citation

Dessen P

AKIP1 (A-kinase interacting protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2011-04-01

Online version: http://atlasgeneticsoncology.org/gene/52192/akip1