KLF3 (Kruppel like factor 3)

2011-09-01  

Identity

HGNC
LOCATION
4p14
LOCUSID
ALIAS
BKLF
FUSION GENES

Other Information

Locus ID:

NCBI: 51274
MIM: 609392
HGNC: 16516
Ensembl: ENSG00000109787

Variants:

dbSNP: 51274
ClinVar: 51274
TCGA: ENSG00000109787
COSMIC: KLF3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000109787ENST00000261438P57682
ENSG00000109787ENST00000261438A0A024R9T8
ENSG00000109787ENST00000514033P57682

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Transcriptional misregulation in cancerKEGGko05202
Transcriptional misregulation in cancerKEGGhsa05202

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
156844032005Role for SUMO modification in facilitating transcriptional repression by BKLF.43
220032052011Impaired B cell development in the absence of Krüppel-like factor 3.25
159376682005Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes.22
214706782011Deregulated expression of Kruppel-like factors in acute myeloid leukemia.22
213606372011The mammalian zinc finger transcription factor Krüppel-like factor 3 (KLF3/BKLF).19
239188072013A feedback loop consisting of microRNA 23a/27a and the β-like globin suppressors KLF3 and SP1 regulates globin gene expression.18
259793692015The role of epigenetics in the endothelial cell shear stress response and atherosclerosis.16
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11

Citation

Dessen P

KLF3 (Kruppel like factor 3)

Atlas Genet Cytogenet Oncol Haematol. 2011-09-01

Online version: http://atlasgeneticsoncology.org/gene/52364/klf3